Institut National de la Santé et de la Recherche Médicale, CR-U1052, Groupe de Radiobiologie, Centre de Recherches en Cancérologie, Lyon.
Int J Radiat Biol. 2013 Jan;89(1):2-8. doi: 10.3109/09553002.2012.717732. Epub 2012 Aug 24.
By extending to other animal models the experiments on irradiated rabbit testes performed by the German Albers-Schönberg and Frieben and inspired by the preliminary observations of Regaud on spermatogenesis after irradiation, Bergonié and Tribondeau established a link between radiosensitivity and proliferation as a 'law' in 1906. Although it is still popular and taken as one of the founding laws of radiation oncology, it was early considered as a 'first approximation'.
More than 100 years later, one tribute paid to these pioneers should be to at least avoid mixing notions like radiosensitivity, proliferation, differentiation, stem cells that they deeply contributed to define and to re-read their works in their original version in order to better understand what the technological and conceptual advances really are today.
通过将德国的 Albers-Schönberg 和 Frieben 对受照射兔睾丸进行的实验扩展到其他动物模型，并受到 Regaud 关于照射后精子发生的初步观察的启发，Bergonié 和 Tribondeau 于 1906 年建立了放射敏感性与增殖之间的联系，将其作为“法则”。尽管它仍然很流行，并被视为放射肿瘤学的基础定律之一，但它很早就被认为是“第一近似值”。
100 多年后，对这些先驱者的一种致敬方式至少应该是避免混淆像放射敏感性、增殖、分化、干细胞这样的概念，这些概念是他们深入定义的，并重新以原文阅读他们的著作，以便更好地了解今天的技术和概念进步到底是什么。
