• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

双侧全角膜上皮糜烂作为细胞毒性疗法的一种副作用。

Bilateral total corneal epithelial erosion as a side effect of cytotoxic therapy.

作者信息

Hirsh A, Alhalel A, Weiss A, Brener H, Avni I

机构信息

Chaim Sheba Medical Center, Tel-Aviv University, Sackler School of Medicine, Israel.

出版信息

Br J Ophthalmol. 1990 Oct;74(10):638. doi: 10.1136/bjo.74.10.638.

DOI:10.1136/bjo.74.10.638
PMID:2285691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042238/
Abstract

Bilateral total corneal epithelial erosion and descement folds are reported as toxic side effects of 5-fluorouracil in a patient with end stage carcinoma of the stomach.

摘要

据报道,一名晚期胃癌患者出现双侧角膜上皮全层糜烂和后弹力层皱襞,这是5-氟尿嘧啶的毒性副作用。

相似文献

1
Bilateral total corneal epithelial erosion as a side effect of cytotoxic therapy.双侧全角膜上皮糜烂作为细胞毒性疗法的一种副作用。
Br J Ophthalmol. 1990 Oct;74(10):638. doi: 10.1136/bjo.74.10.638.
2
Combination therapy with 5-fluorouracil (5-FU; NSC-19893) and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) for disseminated gastrointestinal carcinoma.5-氟尿嘧啶(5-FU;NSC-19893)与1,3-双(2-氯乙基)-1-亚硝基脲(卡莫司汀;NSC-409962)联合治疗播散性胃肠道癌。
Cancer Chemother Rep. 1972 Oct;56(5):653-7.
3
Corneal changes induced by mepacrine.奎宁丁引起的角膜变化。 (注:你原文中的“mepacrine”有误,应该是“quinine”,我按正确的quinine翻译,若必须按错误的“mepacrine”翻译则是“米帕林引起的角膜变化” )
J Trop Med Hyg. 1979 Sep-Oct;82(9-10):206-7.
4
[Chemotherapy of advanced gastric carcinoma with 5-fluorouracil].
Osp Ital Chir. 1968 Aug;19(2):119-22.
5
Chemotherapy-associated peripheral sensory neuropathy assessed using in vivo corneal confocal microscopy.
Arch Neurol. 2010 Mar;67(3):364-5. doi: 10.1001/archneurol.2010.17.
6
[Safety of Hyaluronic Acid in Postoperative Treatment after Penetrating Keratoplasty].[透明质酸在穿透性角膜移植术后治疗中的安全性]
Klin Monbl Augenheilkd. 2018 Jan;235(1):64-72. doi: 10.1055/s-0042-116158. Epub 2016 Oct 6.
7
Comparison of oral ftorafur and intravenous 5-fluorouracil in patients with advanced cancer of the stomach, colon or rectum.口服替加氟与静脉注射5-氟尿嘧啶治疗晚期胃癌、结肠癌或直肠癌患者的比较。
Oncology. 1986;43(4):212-5. doi: 10.1159/000226367.
8
5-fluorouracil therapy for cancer of the stomach.5-氟尿嘧啶治疗胃癌
Cancer. 1967 May;20(5):668-72. doi: 10.1002/1097-0142(1967)20:5<668::aid-cncr2820200516>3.0.co;2-5.
9
A bilateral cicatricial ectropion and bilateral upper lid shortening caused by 5-fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency.
Cutan Ocul Toxicol. 2011 Jun;30(2):157-9. doi: 10.3109/15569527.2010.532846. Epub 2010 Nov 16.
10
Delayed corneal epitheliopathy after antimetabolite-augmented trabeculectomy.抗代谢药物辅助小梁切除术后的延迟性角膜上皮病变
J Glaucoma. 1998 Aug;7(4):237-9.

引用本文的文献

1
Bilateral punctate keratitis and hurricane keratopathy following apremilast therapy.阿普司特治疗后出现双侧点状角膜炎和飓风性角膜病变。
Am J Ophthalmol Case Rep. 2023 Aug 3;32:101905. doi: 10.1016/j.ajoc.2023.101905. eCollection 2023 Dec.
2
Adverse effects of the oral anticancer drug s-1: lacrimal passage impairment and specific features of corneal epitheliopathy.口服抗癌药物S-1的不良反应:泪道损伤及角膜上皮病变的特征
Open Ophthalmol J. 2013 Dec 30;7:85-6. doi: 10.2174/1874364101307010085. eCollection 2013.
3
Graft failure: II. Ocular surface complications.移植物失败:II. 眼表并发症。
Int Ophthalmol. 2008 Jun;28(3):175-89. doi: 10.1007/s10792-007-9127-9.

本文引用的文献

1
Five years clinical experience with 5-fluorouracil.5-氟尿嘧啶的五年临床经验。
JAMA. 1962 Jul 28;181:295-9. doi: 10.1001/jama.1962.03050300015003.
2
Interim report: National Registry of possible Drug-induced Ocular Side Effects.
Ophthalmology. 1980 Feb;87(2):87-90. doi: 10.1016/s0161-6420(80)35263-9.
3
Eye toxicity of cancer chemotherapy: a review of the literature.
Cancer. 1981 Oct 1;48(7):1539-49. doi: 10.1002/1097-0142(19811001)48:7<1539::aid-cncr2820480713>3.0.co;2-b.
4
Ocular toxicity of antineoplastic agents.抗肿瘤药物的眼部毒性。
Ophthalmology. 1983 Jan;90(1):1-3. doi: 10.1016/s0161-6420(83)34600-5.
5
Excessive lacrimation from fluorouracil treatment.
JAMA. 1973 Aug 13;225(7):747-8. doi: 10.1001/jama.1973.03220340051021.
6
Oculomotor disturbances associated with 5-fluorouracil chemotherapy.与5-氟尿嘧啶化疗相关的动眼神经功能障碍。
Am J Ophthalmol. 1977 Jun;83(6):789-93. doi: 10.1016/0002-9394(77)90904-7.
7
Cicatricial ectropion secondary to 5-fluorouracil therapy.
Med Pediatr Oncol. 1977;3(1):15-9. doi: 10.1002/mpo.2950030104.
8
Tear-duct fibrosis (dacryostenosis) due to 5-fluorouracil.5-氟尿嘧啶导致的泪道纤维化(泪道狭窄)。
Ann Intern Med. 1978 May;88(5):657. doi: 10.7326/0003-4819-88-5-657_1.
9
Chemotherapy of gastrointestinal cancer.
Clin Gastroenterol. 1976 Sep;5(3):777-93.