Mataruski M R, Keis N A, Smouse D J, Workman M L
Nurse Anesth. 1990 Dec;1(4):183-8.
The purpose of this study was to determine if the use of intraoperative steroids was effective in decreasing the incidence of postanesthetic nausea and vomiting and whether or not those complications were gender related. This retrospective study involved a chart review of 208 patients undergoing lumbar laminectomy at a large metropolitan hospital during a 10-month period in 1989-1990. Sixty-one patients met inclusion criteria and were accepted into the study. Of these, 34 patients had received an intraoperative steroid; 21 were male and 13 female. Twenty-seven patients did not receive intraoperative steroids; 17 were male and 13 female. Data collected included the number of pain medications and antiemetics used in the postoperative period, as well as the number of episodes of nausea and vomiting in the 24 hours following surgery. Results demonstrated that those patients who received intraoperative steroids were less likely to experience problems of nausea and vomiting than those who did not receive the drug. Requirements for postoperative pain medication were also reduced in the steroid group. Female patients in both groups were shown to have a greater incidence of nausea and vomiting than male patients.
本研究的目的是确定术中使用类固醇是否能有效降低麻醉后恶心和呕吐的发生率，以及这些并发症是否与性别有关。这项回顾性研究涉及对1989年至1990年期间在一家大型都市医院接受腰椎椎板切除术的208例患者的病历进行审查。61例患者符合纳入标准并被纳入研究。其中，34例患者接受了术中类固醇治疗；男性21例，女性13例。27例患者未接受术中类固醇治疗；男性17例，女性13例。收集的数据包括术后使用的止痛药和止吐药的数量，以及术后24小时内恶心和呕吐的发作次数。结果表明，接受术中类固醇治疗的患者比未接受该药物治疗的患者更不容易出现恶心和呕吐问题。类固醇组术后止痛药的需求也有所减少。两组中的女性患者恶心和呕吐的发生率均高于男性患者。
