Am J Gastroenterol. 2012 Aug;107(8):1187-8. doi: 10.1038/ajg.2012.182.
The recent American College of Gastroenterology Guidelines for Colorectal Cancer Screening highlight obese individuals as a high-risk group for colorectal cancer (CRC). In this issue, Okabayashi and colleagues present data from a well-designed and executed meta-analysis demonstrating an increased adenoma risk for a modest increase in body mass index (BMI). Specifically, overweight (BMI≥25) subjects have an increased risk for colorectal adenomas (odds ratio=1.24 (95% confidence interval=1.16-1.33)) as compared with non-overweight subjects. The paper's many strengths include the careful selection of the best studies. These data highlight the importance of screening in obese patients.
最近美国胃肠病学会发布的结直肠癌筛查指南强调肥胖个体是结直肠癌（CRC）的高危人群。在本期杂志中，Okabayashi 及其同事提供了一项精心设计和执行的荟萃分析数据，该分析表明体重指数（BMI）略有增加会增加腺瘤的风险。具体而言，与非超重受试者相比，超重（BMI≥25）受试者结直肠腺瘤的风险增加（比值比=1.24（95%置信区间=1.16-1.33））。该论文的许多优点包括精心选择了最佳研究。这些数据强调了对肥胖患者进行筛查的重要性。
