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强直性脊柱炎的影像学表现。

Imaging in ankylosing spondylitis.

机构信息

Department of Rheumatology, Copenhagen University Hospital at Glostrup, Nordre Ringvej 57, DK-2600 Glostrup, Denmark.

出版信息

Ther Adv Musculoskelet Dis. 2012 Aug;4(4):301-11. doi: 10.1177/1759720X11436240.

Abstract

Imaging is an integral part of the management of patients with ankylosing spondylitis and axial spondyloarthritis. Characteristic radiographic and/or magnetic resonance imaging (MRI) findings are key in the diagnosis. Radiography and MRI are also useful in monitoring the disease. Radiography is the conventional, albeit quite insensitive, gold standard method for assessment of structural damage in spine and sacroiliac joints, whereas MRI has gained a decisive role in monitoring disease activity in clinical trials and practice. MRI may also, if ongoing research demonstrates a sufficient reliability and sensitivity to change, become a new standard method for assessment of structural damage. Ultrasonography allows visualization of peripheral arthritis and enthesitis, but has no role in the assessment of axial manifestations. Computed tomography is a sensitive method for assessment of structural changes in the spine and sacroiliac joints, but its clinical utility is limited due to its use of ionizing radiation and lack of ability to assess the soft tissues. It is exciting that with continued dedicated research and the rapid technical development it is likely that even larger improvements in the use of imaging may occur in the decade to come, for the benefit of our patients.

摘要

影像学检查是强直性脊柱炎和中轴型脊柱关节炎患者管理的重要组成部分。特征性的影像学和/或磁共振成像(MRI)表现是诊断的关键。影像学检查也可用于疾病监测。放射摄影术虽然相当不敏感,但仍是评估脊柱和骶髂关节结构损伤的传统金标准方法,而 MRI 在临床试验和实践中对监测疾病活动具有决定性作用。如果正在进行的研究显示出足够的可靠性和对变化的敏感性,MRI 也可能成为评估结构损伤的新标准方法。超声检查可用于显示外周关节炎和附着点炎,但在评估轴性表现方面没有作用。计算机断层扫描是评估脊柱和骶髂关节结构变化的敏感方法,但由于其使用电离辐射以及缺乏评估软组织的能力,其临床应用受到限制。令人兴奋的是,随着持续的专门研究和快速的技术发展,在未来十年中,影像学的应用可能会有更大的改进,这将使我们的患者受益。

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