Department of Chemistry, University at Buffalo, The State University of New York, Amherst, New York 14260, United States.
Org Lett. 2012 Aug 17;14(16):4178-81. doi: 10.1021/ol301846q. Epub 2012 Aug 6.
A relay strategy was employed to achieve an intermolecular ene-yne metathesis between 1,1-disubstituted alkenes and alkynes. The relay serves to activate an unreactive alkene which will not participate in ene-yne metathesis. The new relay cross ene-yne metathesis gives rise to 1,1,3-trisubstituted-1,3-dienes previously inaccessible by direct ene-yne metathesis methods.
采用接力策略实现了 1,1-二取代烯烃和炔烃的分子间烯炔复分解反应。该接力反应可以激活不参与烯炔复分解反应的惰性烯烃。新的接力交叉烯炔复分解反应得到了 1,1,3-三取代-1,3-二烯，这是以前直接烯炔复分解方法无法获得的。
