Costa P, Benna P, Bianco C, Ferrero P, Bergamasco B
Department of Neurology, University of Turin, Italy.
Electromyogr Clin Neurophysiol. 1990 Dec;30(8):495-500.
Since age effects on central conduction time in the acoustic pathway are still debated, we recorded brainstem auditory evoked potentials in 154 normoacoustic subjects, with no history of neurologic or otologic pathology. Linear regression has been used for statistical analysis. Data obtained show an age-related prolongation of latency values which is particularly marked for wave I, while other waves (particularly wave III) do not show a significant change. Thus, interpeak latency (IPL) values do not increase with increasing age: in particular IPLs I-II and I-III decrease, showing a negative "r" value, and IPLs I-V and II-V (which is to be considered the true "central conduction time" through the acoustic pathway) do not show a significant change. Our data seem to demonstrate that the aging process is essentially a peripheral phenomenon which does not involve the central part of the acoustic pathway.
由于年龄对听觉通路中枢传导时间的影响仍存在争议，我们对154名听力正常、无神经或耳科疾病史的受试者记录了脑干听觉诱发电位。采用线性回归进行统计分析。获得的数据显示潜伏期值随年龄增长而延长，这在I波尤为明显，而其他波（特别是III波）没有显著变化。因此，峰间潜伏期（IPL）值不会随年龄增长而增加：特别是I-II和I-III的IPL值下降，显示出负的“r”值，而I-V和II-V的IPL值（应被视为通过听觉通路的真正“中枢传导时间”）没有显著变化。我们的数据似乎表明，衰老过程本质上是一种外周现象，不涉及听觉通路的中枢部分。
