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基于在线群组的认知行为疗法在癌症治疗后用于青少年和年轻成人:Recapture Life-AYA 的多中心随机对照试验。

Online group-based cognitive-behavioural therapy for adolescents and young adults after cancer treatment: a multicenter randomised controlled trial of Recapture Life-AYA.

机构信息

Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick, NSW, Australia.

出版信息

BMC Cancer. 2012 Aug 3;12:339. doi: 10.1186/1471-2407-12-339.

Abstract

BACKGROUND

A cancer diagnosis is 2.9 times more likely to occur during the adolescent and young adult years than in younger children. This spike in incidence coincides with a life stage characterised by psychological vulnerability as young people strive to attain numerous, critical developmental milestones. The distress young people experience after cancer treatment seriously jeopardises their ability to move into well-functioning adulthood.

METHODS/DESIGN: This article presents the protocol of the Recapture Life study, a phase II three-arm randomised controlled trial designed to evaluate the feasibility and efficacy of a new intervention in reducing distress and improving quality of life for adolescent and young adult cancer survivors. The novel intervention, "ReCaPTure LiFe" will be compared to a both a wait-list, and a peer-support group control. Ninety young people aged 15-25 years who have completed cancer treatment in the past 1-6 months will be recruited from hospitals around Australia. Those randomised to receive Recapture Life will participate in six, weekly, 90-minute online group sessions led by a psychologist, involving peer-discussion around cognitive-behavioural coping skills (including: behavioural activation, thought challenging, communication and assertiveness skills training, problem-solving and goal-setting). Participants randomised to the peer-support group control will receive non-directive peer support delivered in an identical manner. Participants will complete psychosocial measures at baseline, post-intervention, and 12-months post-intervention. The primary outcome will be quality of life. Secondary outcomes will include depression, anxiety, stress, family functioning, coping, and cancer-related identity.

DISCUSSION

This article reviews the empirical rationale for using group-based, online cognitive-behavioural therapy in young people after cancer treatment. The potential challenges of delivering skills-based programs in an online modality are highlighted, and the role of both peer and caregiver support in enhancing the effectiveness of this skills-based intervention is also discussed. The innovative videoconferencing delivery method Recapture Life uses has the potential to address the geographic and psychological isolation of adolescents and young adults as they move toward cancer survivorship. It is expected that teaching AYAs coping skills as they resume their normal lives after cancer may have long-term implications for their quality of life.

TRIAL REGISTRATION

ACTRN12610000717055.

摘要

背景

青少年和年轻成年人患癌症的几率比年幼儿童高 2.9 倍。这种发病率的上升与年轻人努力实现众多关键发展里程碑的心理脆弱阶段相吻合。癌症治疗后年轻人所经历的痛苦严重危及他们步入正常成年生活的能力。

方法/设计:本文介绍了 Recapture Life 研究的方案,这是一项旨在评估新干预措施减少青少年和年轻成年癌症幸存者痛苦和提高生活质量的可行性和疗效的 II 期三臂随机对照试验。新的干预措施“ReCaPTure LiFe”将与等待名单和同伴支持组对照进行比较。将从澳大利亚各地的医院招募 90 名年龄在 15-25 岁之间、过去 1-6 个月内完成癌症治疗的年轻人。那些被随机分配接受 Recapture Life 的人将参加六次每周 90 分钟的在线小组会议,由心理学家主持,包括围绕认知行为应对技能(包括行为激活、思维挑战、沟通和自信技能训练、解决问题和设定目标)进行同伴讨论。随机分配到同伴支持组对照的参与者将以相同的方式接受非指导性的同伴支持。参与者将在基线、干预后和干预后 12 个月完成心理社会测量。主要结果将是生活质量。次要结果将包括抑郁、焦虑、压力、家庭功能、应对和癌症相关身份。

讨论

本文回顾了在癌症治疗后对年轻人使用基于群体的在线认知行为疗法的实证依据。强调了在线模式下提供技能方案的潜在挑战,并讨论了同伴和照顾者支持在增强这种基于技能的干预措施的有效性方面的作用。Recapture Life 使用的创新视频会议交付方法有可能解决青少年和年轻成年人在走向癌症生存者时所面临的地理和心理孤立问题。人们希望,在癌症后年轻人恢复正常生活时教授他们应对技能,可能对他们的生活质量产生长期影响。

试验注册

ACTRN12610000717055。

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