Suppr超能文献

[营养在肿瘤学中的相关性是什么?]

[What is the relevance of nutrition in oncology?].

作者信息

de Carvalho Gustavo, Camilo Maria Ermelinda, Ravasco Paula

机构信息

Laboratório de Nutrição/Unidade de Nutrição e Metabolismo, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.

出版信息

Acta Med Port. 2011 Dec;24 Suppl 4:1041-50. Epub 2011 Dec 31.

Abstract

Cancer has an increasingly significant impact on society, being a highly destabilizing factor in the life of any patient. The disease as well as anti-neoplastic treatments can profoundly alter biological functions and, remarkably, the patients' nutritional status. Thus, Nutrition is a key factor in oncology, by influencing the development of the disease, cancer related symptoms, the response to, and recovery from treatment(s), and therefore determining the patients' Quality of Life and probably prognosis. Therefore, the assessment of Quality of Life in any clinical study is essential because it values physical, psychological and social factors, which often depend on or are related with Nutrition. The aim of this review work, was to explore extent to which individualized nutrition intervention improves nutritional parameters (nutritional status and intake), Quality of Life, and ultimately the prognosis of the disease. Based on clinical research studies conducted until now, early nutritional intervention via individualized nutritional counseling, does significantly improve nutritional parameters and Quality of Life. It was also found that appropriate and individualized nutritional intervention, improves symptoms, reduces morbidity and may have the potential to improve the prognosis of the disease. According to the reviewed data and guidelines, nutritional therapy should be central and adjuvant to any treatment, and should be included in the multidisciplinary approach mandatory in oncology. This will allow for more adequate and efficient results these patients. Multidisciplinary follow-up, with early nutritional intervention, is of major importance in oncology, thus being a key factor for successful treatment and recovery of these patients.

摘要

癌症对社会的影响日益显著,是任何患者生活中极具不稳定的因素。该疾病以及抗肿瘤治疗会深刻改变生物学功能,而且显著影响患者的营养状况。因此,营养在肿瘤学中是一个关键因素,它会影响疾病的发展、癌症相关症状、对治疗的反应以及治疗后的恢复情况,进而决定患者的生活质量以及可能的预后。所以,在任何临床研究中评估生活质量都至关重要,因为它重视身体、心理和社会因素,而这些因素往往取决于营养或与营养相关。本综述工作的目的是探讨个体化营养干预在多大程度上能改善营养参数(营养状况和摄入量)、生活质量,并最终改善疾病的预后。基于目前已开展的临床研究,通过个体化营养咨询进行早期营养干预,确实能显著改善营养参数和生活质量。研究还发现,适当的个体化营养干预能改善症状、降低发病率,并且可能有改善疾病预后的潜力。根据综述数据和指南,营养治疗应是任何治疗的核心和辅助手段,应纳入肿瘤学中必不可少的多学科治疗方法。这将使这些患者获得更充分和有效的治疗效果。多学科随访以及早期营养干预在肿瘤学中至关重要,因此是这些患者成功治疗和康复的关键因素。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验