Dada T, Bali S J, Mohan S, Bhartiya S, Sobti A, Panda A
Dr Rajendra Prasad Centre for Ophthalmic sciences, AIIMS, New Delhi, India.
Nepal J Ophthalmol. 2012 Jul-Dec;4(2):224-9. doi: 10.3126/nepjoph.v4i2.6536.
To report the use of trypan blue staining of the filtering bleb to assess its functional status in eyes undergoing phacoemulsification after trabeculectomy.
This retrospective study was conducted at a tertiary eye care centre in North India and studied 33 eyes of 33 patients ( with previously operated trabeculectomy), who underwent phacoemulsification. Trypan blue dye (0.06%) was used to stain the anterior capsule. After completion of phacoemulsification, the staining of the trabeculectomy bleb was noted as diffuse, patchy, minimal or no staining.
Of the 33 eyes, 13 had diffuse staining (39.4%, mean IOP = 9.3 ± 2.2 mm Hg), 7 (21.2%, mean IOP= 15.5 ± 1.8 mm Hg) had patchy staining, 4 had minimal staining (12.1%, mean IOP= 17.5 ± 0.5mm Hg) and nine (27.3%, mean IOP= 19.3 ± 1.6 mm Hg) had no staining. These staining patterns were labeled as groups 1 - 4 respectively. Statistical analysis showed that the difference between the IOPs in Group 1 - 2 and between Group 2 - 3 was not significant statistically (p=0.682 and 0.665 respectively). However the differences between the IOPs between Groups 1 - 3, 1 - 4, 2 - 4, and 3 - 4 were found to be highly significant statistically (p less than 0.0005).
Trypan blue dye can be used to test the amount of sub conjunctival filtration in eyes undergoing phacoemulsification cataract surgery.
报告使用锥蓝对滤过泡进行染色，以评估小梁切除术后接受白内障超声乳化术的眼睛的滤过泡功能状态。
这项回顾性研究在印度北部的一家三级眼科护理中心进行，研究对象为33例（曾接受小梁切除术）接受白内障超声乳化术的患者的33只眼睛。使用锥蓝染料（0.06%）对前囊膜进行染色。白内障超声乳化术完成后，观察小梁切除滤过泡的染色情况，分为弥漫性、斑片状、轻微染色或无染色。
33只眼中，13只出现弥漫性染色（39.4%，平均眼压 = 9.3 ± 2.2 mmHg），7只（21.2%，平均眼压 = 15.5 ± 1.8 mmHg）出现斑片状染色，4只出现轻微染色（12.1%，平均眼压 = 17.5 ± 0.5 mmHg），9只（27.3%，平均眼压 = 19.3 ± 1.6 mmHg）无染色。这些染色模式分别标记为1 - 4组。统计分析表明，第1 - 2组之间以及第2 - 3组之间的眼压差异无统计学意义（分别为p = 0.682和0.665）。然而，发现第1 - 3组、1 - 4组、2 - 4组和3 - 4组之间的眼压差异具有高度统计学意义（p小于0.0005）。
锥蓝染料可用于测试接受白内障超声乳化手术的眼睛结膜下滤过的量。
