Lions Eye Institute, University of Western Australia, Nedlands, Western Australia, Australia.
Department of Ophthalmology, Faculty of Medicine, Brawijaya University Dr Saiful Anwar General Hospital, Malang, Indonesia.
Clin Exp Ophthalmol. 2019 Sep;47(7):892-897. doi: 10.1111/ceo.13534. Epub 2019 May 27.
To illustrate the importance of lymphatic drainage in assessing trabeculectomy bleb function using intracameral trypan blue.
To study the lymphatic drainage of trabeculectomy blebs using trypan blue, correlate with bleb function and classify them accordingly.
Prospective cross-sectional study in a tertiary care centre.
Thirteen glaucoma patients post-trabeculectomy were studied.
Trypan blue was injected into the anterior chamber.
The duration taken for dye to stain a drainage bleb or lymphatics is recorded. The extent of the lymphatic structures were measured in clock hours. Intraocular pressure (IOP) prior to surgery was recorded.
Eight post-trabeculectomy subjects with dye stained lymphatic vessels had lower IOP (12.6 mmHg, P = .013) compared to the five with no lymphatic vessel staining (mean IOP 23.6 mmHg). Lymphatic extent was inversely related to IOP (P = .021).
Eyes with lymphatic connections to drainage blebs had lower IOP and reduced requirement for topical medications. The extent of lymphatic connection to drainage blebs is related to lower IOP.
使用眼内注射台盼蓝来评估小梁切除术滤泡功能，以说明淋巴引流的重要性。
使用台盼蓝研究小梁切除术滤泡的淋巴引流，与滤泡功能相关联，并进行相应的分类。
在三级保健中心进行的前瞻性横断面研究。
13 例青光眼患者行小梁切除术。
将台盼蓝注射到前房。
染料染色引流滤泡或淋巴管所需的时间记录。淋巴结构的范围以时钟小时测量。术前记录眼内压（IOP）。
8 例小梁切除术后有染料染色淋巴管的受试者的 IOP 较低（12.6mmHg，P=0.013），而 5 例无淋巴管染色的受试者的 IOP 较高（平均 IOP 23.6mmHg）。淋巴范围与 IOP 呈负相关（P=0.021）。
与引流滤泡有淋巴联系的眼睛的 IOP 较低，对局部药物的需求减少。引流滤泡的淋巴联系程度与较低的 IOP 相关。
