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尿路感染的流行病学及显著菌尿的概念。

The epidemiology of urinary tract infection and the concept of significant bacteriuria.

作者信息

Hooton T M

机构信息

Department of Medicine, University of Washington, Seattle 98104.

出版信息

Infection. 1990;18 Suppl 2:S40-3. doi: 10.1007/BF01643424.

DOI:10.1007/BF01643424
PMID:2286458
Abstract

Urinary tract infections (UTI) are among the most common infections afflicting man. Urinary tract infections in young adult women are usually uncomplicated, but are often recurrent and cause considerable morbidity. Urinary tract infections in pregnant women, elderly patients, and catheterized patients warrant special attention because of their association with increased morbidity and possibly with increased mortality. Diagnosis of UTI is usually based on quantitation of uropathogens in voided urine. The traditional criteria for significant bacteriuria, greater than or equal to 10(5) uropathogens per ml of voided urine, is insensitive for detecting acute symptomatic cystitis in men and women and should be replaced with a lower colony count threshold.

摘要

尿路感染(UTI)是困扰人类的最常见感染之一。年轻成年女性的尿路感染通常并不复杂,但往往会反复发作,并导致相当高的发病率。孕妇、老年患者和留置导尿管患者的尿路感染因其与发病率增加以及可能的死亡率增加相关而值得特别关注。UTI的诊断通常基于对排尿中尿路病原体的定量。传统的显著菌尿标准,即每毫升排尿中尿路病原体大于或等于10⁵,对于检测男性和女性的急性症状性膀胱炎并不敏感,应该用更低的菌落计数阈值来取代。

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本文引用的文献

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Recurrent infection of the urinary tract: reinfection or recrudescence?复发性尿路感染:再感染还是复发?
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Bacteriuria and pyelonephritis of pregnancy.妊娠期菌尿症和肾盂肾炎
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Lower serum levels of vitamin D in adults with urinary tract infection.成年人尿路感染时血清维生素 D 水平较低。
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Intermittent catheterization and recurrent urinary tract infection in spinal cord injury.脊髓损伤患者的间歇性导尿与复发性尿路感染
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Clinical significance of bacteriuria with low colony counts of Enterococcus species.肠球菌属低菌落计数菌尿的临床意义
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8
Fosfomycin tromethamine. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy as a single-dose oral treatment for acute uncomplicated lower urinary tract infections.磷霉素氨丁三醇。对其抗菌活性、药代动力学特性以及作为急性单纯性下尿路感染单剂量口服治疗的疗效的综述。
Drugs. 1997 Apr;53(4):637-56. doi: 10.2165/00003495-199753040-00007.
9
Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.依诺沙星:对其治疗泌尿生殖道感染临床疗效的重新评估。
Drugs. 1996 Jan;51(1):137-60. doi: 10.2165/00003495-199651010-00009.
10
Diagnostic regimes for urinary tract infection--are research results applied to practice?尿路感染的诊断方案——研究结果是否应用于实践?
Ulster Med J. 1995 Oct;64(2):131-6.
Am J Med. 1955 May;18(5):764-81. doi: 10.1016/0002-9343(55)90190-x.
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Prevention of apparently non-infectious disease by detection and treatment of infections of the urinary tract.
J Chronic Dis. 1962 Jul;15:665-73. doi: 10.1016/0021-9681(62)90019-x.
5
A comparison of bacterial counts of the urine obtained by needle aspiration of the bladder, catheterization and midstream-voided methods.膀胱穿刺抽吸法、导尿法和清洁中段尿法所获尿液细菌计数的比较。
N Engl J Med. 1958 Oct 16;259(16):764-7. doi: 10.1056/NEJM195810162591603.
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Asymptomatic infections of the urinary tract.无症状性尿路感染
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1985 Summary: National Ambulatory Medical Care Survey.1985年总结:国家门诊医疗护理调查
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The association of urinary tract infection with sexual intercourse.尿路感染与性交的关联。
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Mortality associated with nosocomial urinary-tract infection.与医院获得性尿路感染相关的死亡率
N Engl J Med. 1982 Sep 9;307(11):637-42. doi: 10.1056/NEJM198209093071101.
10
Diagnosis of coliform infection in acutely dysuric women.急性排尿困难女性大肠菌感染的诊断
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