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挪威白种人中HLA II类等位基因的分布。

Distribution of HLA class II alleles among Norwegian Caucasians.

作者信息

Rønningen K S, Spurkland A, Markussen G, Iwe T, Vartdal F, Thorsby E

机构信息

Institute of Transplantation Immunology, National Hospital, Oslo, Norway.

出版信息

Hum Immunol. 1990 Dec;29(4):275-81. doi: 10.1016/0198-8859(90)90041-m.

DOI:10.1016/0198-8859(90)90041-m
PMID:2286539
Abstract

We report genomic HLA class II typing of 181 randomly selected Norwegian controls. Seventeen DRB1, 7 DQA1, 10 DQB1, 2 DPA1, and 16 DPB1 alleles were found in the tested population. HLA class II antigen and allele frequencies are given, as well as the distribution of DRB1, DQA1, DQB1 haplotypes. Linkage disequilibrium between some DPB1 alleles and DRB1 and/or DQB1 alleles are also reported.

摘要

我们报告了对181名随机选择的挪威对照进行的基因组HLA II类分型。在受试人群中发现了17个DRB1、7个DQA1、10个DQB1、2个DPA1和16个DPB1等位基因。给出了HLA II类抗原和等位基因频率,以及DRB1、DQA1、DQB1单倍型的分布情况。还报告了一些DPB1等位基因与DRB1和/或DQB1等位基因之间的连锁不平衡情况。

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