Singh V K, Sharma M, Rohatgi P
GSVM Medical College, Kanpur.
J Indian Med Assoc. 1990 Sep;88(9):253-4.
Salbutamol, a beta-adrenergic stimulant, with a property of smooth muscle inhibition has been used in prevention of premature labour on 40 patients. To 540 ml of 5% dextrose solution 5 mg of salbutamol was added. The infusion was started at the rate of 10 drops per minute and then increased by 10 drops every 5-10 minutes, until uterine contractions ceased. It was observed that in 62.5% patients pregnancy was prolonged for more than 7 days and in 80% for more than 3 days. The mean gain in days was 14.8 days and the maximum was 48 days. The drug was more effective in patients with cervical dilatation less than 2 cm and with uterine contractions less than 3 per 10 minutes.
沙丁胺醇是一种β-肾上腺素能兴奋剂，具有平滑肌抑制特性，已用于40例患者预防早产。在540毫升5%葡萄糖溶液中加入5毫克沙丁胺醇。以每分钟10滴的速度开始输注，然后每5 - 10分钟增加10滴，直至子宫收缩停止。观察到62.5%的患者妊娠延长超过7天，80%的患者延长超过3天。平均延长天数为14.8天，最长为48天。该药物在宫颈扩张小于2厘米且子宫收缩每10分钟少于3次的患者中更有效。
