Shintani Takuji, Fujioka Yasutada, Takeuchi Toshifumi
Department of Cardiovascular Surgery, Rakuwakai-Otowa Hospital, Kyoto, Japan.
Kyobu Geka. 2012 Aug;65(9):800-3.
It has been reported that cardiac resynchronization therapy( CRT) improves cardiac systolic function and reverses cardiac remodeling by correcting intra- and interventricular asynchrony, and that mitral valve replacement (MVR) with bileaflet preservation dose not impair left ventricular systolic function through preserving the continuity of the mitral complex.The present report describes a case of a 68-year-old female with severe chronic heart failure and mitral valve regurgitation due to end-stage dilated cardiomyopathy who showed improved exercise tolerance following CRT and MVR with bileaflet preservation. Based on this case, we considered that the combination therapy of CRT and MVR with bileaflet preservation might be one of the effective strategies for severe chronic heart failure and mitral valve regurgitation due to end-stage dilated cardiomyopathy.
据报道,心脏再同步治疗(CRT)通过纠正心室内和心室间不同步来改善心脏收缩功能并逆转心脏重塑,并且保留双叶的二尖瓣置换术(MVR)通过保持二尖瓣复合体的连续性不会损害左心室收缩功能。本报告描述了一例68岁女性患者,患有严重慢性心力衰竭和终末期扩张型心肌病所致二尖瓣反流,在接受CRT和保留双叶的MVR治疗后运动耐量得到改善。基于该病例,我们认为CRT与保留双叶的MVR联合治疗可能是治疗终末期扩张型心肌病所致严重慢性心力衰竭和二尖瓣反流的有效策略之一。