Department of Orthopedic Surgery, Rady Children's Hospital and Health Center, San Diego, CA, USA.
Spine (Phila Pa 1976). 2013 Feb 15;38(4):328-38. doi: 10.1097/BRS.0b013e31826c6df4.
Prospective, consecutive, nonrandomized, multicenter study.
The purpose of this study was to compare the outcomes of idiopathic scoliosis treatment for Lenke 1 curves with 3 treatment approaches.
Surgical treatment options for Lenke 1 or primary main thoracic curve pattern in adolescent idiopathic scoliosis include thoracoscopic anterior spinal fusion, open anterior spinal fusion, and posterior spinal fusion (PSF) and instrumentation procedures.
This was a prospective, consecutive, nonrandomized, multicenter study of surgical correction in adolescent idiopathic scoliosis. Patients with Lenke type 1 curve patterns from 7 sites were enrolled in this minimum 2-year follow-up study. Changes in pre- to postoperative radiographs, pulmonary function tests, Scoliosis Research Society questionnaire scores, and trunk rotation measures were compared.
A total of 149 patients (age: 14.5 ± 2 yr) were included (91% follow-up at 2 yr). The 3 groups were similar preoperatively in thoracic and lumbar curve size. There were 55 patients with thoracoscopic anterior spinal fusion, 17 patients with open anterior spinal fusion, and 64 patients with PSF. The fusion included on average 3 to 4 more levels in PSF than the 2 anterior approaches (P ≤ 0.001). Surgical time tended to be greater in the anterior groups by approximately 2 to 3 hours; however, blood loss was greatest with PSF. At 2 years, all 3 approaches showed similar improvements in the thoracic Cobb angle, coronal balance, the lumbar Cobb angle, Scoliosis Research Society questionnaire scores, and trunk rotation measures. The PSF approach resulted in overall reduction in kyphosis compared with the anterior approaches. Postoperative hyperkyphosis was an issue only in the 2 anterior groups. Major complication rates were similar.
All 3 approaches resulted in similarly satisfactory outcomes for the majority of patients with specific advantages to each technique. The patients with PSF had more levels fused, yet with the shortest operative time. The thoracoscopic anterior spinal fusion group had the smallest incisions and the lowest requirement for transfusion. The open anterior spinal fusion group had a modest loss of pulmonary function without any clear advantages compared with the other 2 groups.
前瞻性、连续、非随机、多中心研究。
本研究旨在比较三种治疗方法治疗特发性脊柱侧凸 Lenke 1 型曲线的结果。
青少年特发性脊柱侧凸中 Lenke 1 或原发性主胸曲的手术治疗选择包括胸腔镜前路脊柱融合术、前路开放脊柱融合术和后路脊柱融合(PSF)和器械治疗。
这是一项青少年特发性脊柱侧凸后路矫正的前瞻性、连续、非随机、多中心研究。来自 7 个地点的 Lenke 1 型曲线患者参加了这项至少 2 年随访研究。比较了术前至术后影像学、肺功能测试、脊柱侧凸研究协会问卷评分和躯干旋转测量的变化。
共纳入 149 例患者(年龄:14.5±2 岁)(91%在 2 年时随访)。三组患者术前胸腰段曲线大小相似。胸腔镜前路脊柱融合组 55 例,前路开放脊柱融合组 17 例,PSF 组 64 例。PSF 组融合平均比前两种方法多融合 3-4 个节段(P≤0.001)。手术时间在前路组大约长 2-3 小时,但 PSF 组失血最多。2 年后,三种方法在胸弯 Cobb 角、冠状平衡、腰弯 Cobb 角、脊柱侧凸研究协会问卷评分和躯干旋转测量方面均显示出相似的改善。PSF 方法与前路方法相比,总体上降低了后凸角度。后凸角度增加仅见于前两种方法。主要并发症发生率相似。
对于大多数患者来说,三种方法都取得了相似的满意结果,每种方法都有其特定的优势。PSF 组融合的节段较多,但手术时间最短。胸腔镜前路脊柱融合组切口最小,输血需求最低。前路开放脊柱融合组的肺功能略有下降,但与其他两组相比没有明显优势。
2 级。