Lock Michael, Sinclair Kevin, Welch Stephen, Younus Jawaid, Salim Mohammad
Division of Radiation Oncology, London Regional Cancer Program, London, Ontario N6A 4L6, Canada.
Oncol Lett. 2011 Jan;2(1):85-90. doi: 10.3892/ol.2010.195. Epub 2010 Oct 5.
Radiation recall is common following treatment with certain chemotherapy drugs and presents frequently as a skin reaction. With gemcitabine, such a recall phenomenon may affect internal tissues and presents itself as myositis. Although such reactions have previously been reported in the literature, whether or not to continue chemotherapy during such reactions remains controversial. We reported a case of radiation recall in a patient treated with gemcitabine and radiation therapy that presented as myositis. We were able to continue palliative chemotherapy and manage the side effects with supportive care treatment. This case report provides partial support for the continuation of chemotherapy when required even when a recall reaction is encountered.
在使用某些化疗药物治疗后，放射性回忆反应很常见，且常表现为皮肤反应。使用吉西他滨时，这种回忆现象可能会影响内部组织，并表现为肌炎。尽管此前文献中已有此类反应的报道，但在出现此类反应时是否继续化疗仍存在争议。我们报告了一例接受吉西他滨和放射治疗的患者出现放射性回忆反应并表现为肌炎的病例。我们能够继续进行姑息性化疗，并通过支持性护理治疗来管理副作用。本病例报告为即使遇到回忆反应时在必要情况下继续化疗提供了部分支持。
