Ravishankar Adarsh, Park Sean S, Olivier Kenneth R, Corbin Kimberly S
University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Division of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, USA.
Case Rep Oncol. 2018 Mar 27;11(1):168-178. doi: 10.1159/000487478. eCollection 2018 Jan-Apr.
Gemcitabine-induced radiation recall (GIRR) is a phenomenon wherein the administration of gemcitabine induces an inflammatory reaction within an area of prior radiation. We present the case of a 39-year-old female patient with metastatic breast cancer who experienced GIRR myositis 3 months following postoperative radiotherapy, with additional potential paraspinal myositis following ablative radiotherapy to the thoracic spine. A review of previously published cases of GIRR myositis was performed. The case and literature review describe the clinical course and presentation of GIRR, and highlight the importance of including radiation recall as part of a differential diagnosis when a patient undergoing chemotherapy experiences an inflammatory reaction at a prior site of radiation.
吉西他滨诱导的放射回忆反应（GIRR）是一种现象，即给予吉西他滨会在先前放疗区域内引发炎症反应。我们报告了一例39岁转移性乳腺癌女性患者的病例，该患者在术后放疗3个月后出现GIRR性肌炎，在胸椎进行消融放疗后还可能出现椎旁肌炎。我们对先前发表的GIRR性肌炎病例进行了回顾。该病例及文献回顾描述了GIRR的临床过程和表现，并强调当接受化疗的患者在先前放疗部位出现炎症反应时，将放射回忆反应纳入鉴别诊断的重要性。
