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副肿瘤性脑脊髓炎:它是口咽癌还是肺癌的并发症?

Paraneoplastic encephalomyelitis: Is it an oropharyngeal or a lung cancer complication?

作者信息

Moyano María Sereno, Gutiérrez-Gutiérrez Gerardo, Gómez-Raposo César, Gómez Miriam López, Ojeda Joaquín, Miralles Ambrosio, Casado-Sáenz Enrique

机构信息

Department of Oncology, Infanta Sofía Hospital, San Sebastián de los Reyes, Madrid, Spain.

出版信息

Oncol Lett. 2011 Jan;2(1):171-174. doi: 10.3892/ol.2010.224. Epub 2010 Nov 23.

Abstract

This case report describes a patient with a locally advanced oropharyngeal cancer with a simultaneous paraneoplastic encephalomyelitis. To the best of our knowledge, a paraneoplastic neurological syndrome is a rare complication in head and neck cancer, and has previously not been reported in the literature. One year later, following initial treatment, a small cell lung cancer developed, a tumor frequently associated with this type of paraneoplastic syndrome. The dilemma, therefore, is whether this paraneoplastic symdrome was a secondary complication of the tonsilar concurrent cancer or a metachronous paraneoplastic syndrome prior to small cell lung cancer.

摘要

本病例报告描述了一名患有局部晚期口咽癌并同时伴有副肿瘤性脑脊髓炎的患者。据我们所知,副肿瘤性神经综合征是头颈癌中一种罕见的并发症,此前文献中未曾有过报道。一年后,在初始治疗后,患者又患上了小细胞肺癌,这是一种常与这类副肿瘤综合征相关的肿瘤。因此,难题在于这种副肿瘤综合征是扁桃体同时性癌的继发性并发症,还是小细胞肺癌之前的异时性副肿瘤综合征。

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本文引用的文献

2
Paraneoplastic neurological syndromes.副肿瘤性神经系统综合征
Orphanet J Rare Dis. 2007 May 4;2:22. doi: 10.1186/1750-1172-2-22.
4
Cancer of the oropharynx.
Crit Rev Oncol Hematol. 2002 Jan;41(1):107-22. doi: 10.1016/s1040-8428(01)00129-9.
5
Neurologic disorders in patients with small cell lung cancer.小细胞肺癌患者的神经系统疾病
Cancer. 1987 Nov 1;60(9):2275-83. doi: 10.1002/1097-0142(19871101)60:9<2275::aid-cncr2820600929>3.0.co;2-3.

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