Gotera Nico, Schultheis Christian P
Internal Medicine Residency, MercyOne North Iowa Medical Center, Mason City, USA.
Hematology and Medical Oncology, Mission Cancer + Blood, Des Moines, USA.
Cureus. 2022 Apr 20;14(4):e24302. doi: 10.7759/cureus.24302. eCollection 2022 Apr.
Paraneoplastic neurologic syndromes are a set of rare neurological conditions with a wide variety of presentations, ranging from headache to gait imbalance. These conditions are often underreported and underdiagnosed. Paraneoplastic rhombencephalitis is a subtype that involves inflammation of the hindbrain. This case involves a 67-year-old female with metastatic small-cell lung cancer who acutely developed neurological symptoms with magnetic resonance imaging findings consistent with rhombencephalitis. Our case discusses the updated diagnostic criteria for paraneoplastic neurologic syndrome released in July 2021 compared with the prior criteria in 2004. In addition, it illustrates the importance of increasing awareness of this condition for early diagnosis and prompt treatment, which can potentially influence morbidity outcomes.
副肿瘤性神经系统综合征是一组罕见的神经系统疾病，表现形式多种多样，从头痛到步态失衡不等。这些疾病常常报告不足且诊断不足。副肿瘤性菱形脑炎是一种涉及后脑炎症的亚型。本病例涉及一名67岁患有转移性小细胞肺癌的女性，她急性出现神经系统症状，磁共振成像结果与菱形脑炎相符。我们的病例讨论了2021年7月发布的副肿瘤性神经系统综合征的更新诊断标准，并与2004年的先前标准进行了比较。此外，它还说明了提高对这种疾病的认识对于早期诊断和及时治疗的重要性，这可能会影响发病结果。
