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住进置管率较高的医院的晚期认知障碍患者的生存率是否得到提高?

Do patients with advanced cognitive impairment admitted to hospitals with higher rates of feeding tube insertion have improved survival?

机构信息

Program in Public Health, Department of Health Services, Policy & Practice, Brown University, Providence, RI 02912, USA.

出版信息

J Pain Symptom Manage. 2013 Mar;45(3):524-33. doi: 10.1016/j.jpainsymman.2012.02.007. Epub 2012 Aug 4.

DOI:10.1016/j.jpainsymman.2012.02.007
PMID:22871537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3594461/
Abstract

CONTEXT

Research is conflicting on whether receiving medical care at a hospital with more aggressive treatment patterns improves survival.

OBJECTIVES

The aim of this study was to examine whether nursing home residents admitted to hospitals with more aggressive patterns of feeding tube insertion had improved survival.

METHODS

Using the 1999-2007 Minimum Data Set matched to Medicare claims, we identified hospitalized nursing home residents with advanced cognitive impairment who did not have a feeding tube inserted prior to their hospital admissions. The sample included 56,824 nursing home residents and 1773 acute care hospitals nationwide. Hospitals were categorized into nine groups based on feeding tube insertion rates and whether the rates were increasing, staying the same, or decreasing between the periods of 2000-2003 and 2004-2007. Multivariate logit models were used to examine the association between the hospital patterns of feeding tube insertion and survival among hospitalized nursing home residents with advanced cognitive impairment.

RESULTS

Nearly one in five hospitals (N=366) had persistently high rates of feeding tube insertion. Being admitted to these hospitals with persistently high rates of feeding tube insertion was not associated with improved survival when compared with being admitted to hospitals with persistently low rates of feeding tube insertion. The adjusted odds ratios were 0.93 (95% confidence interval [CI]: 0.87, 1.01) and 1.02 (95% CI: 0.95, 1.09) for one-month and six-month posthospitalization survival, respectively.

CONCLUSION

Hospitals with more aggressive patterns of feeding tube insertion did not have improved survival for hospitalized nursing home residents with advanced cognitive impairment.

摘要

背景

研究结果对在治疗模式更激进的医院接受治疗是否能提高生存率存在争议。

目的

本研究旨在检验入住治疗模式更激进的医院的养老院居民的生存率是否有所提高。

方法

利用 1999-2007 年最低数据组与医疗保险索赔相匹配,我们确定了患有严重认知障碍且在入院前未插入饲管的住院养老院居民。该样本包括全国范围内 56824 名养老院居民和 1773 家急性护理医院。根据饲管插入率以及这些率在 2000-2003 年和 2004-2007 年期间是增加、保持不变还是减少,将医院分为 9 组。采用多变量逻辑回归模型检验在严重认知障碍的住院养老院居民中,医院饲管插入模式与生存之间的关联。

结果

近五分之一的医院(N=366)饲管插入率持续较高。与饲管插入率持续较低的医院相比,入住这些饲管插入率持续较高的医院与生存率提高无关。调整后的比值比分别为 0.93(95%置信区间[CI]:0.87,1.01)和 1.02(95%CI:0.95,1.09),用于评估一个月和六个月的住院后生存率。

结论

对于患有严重认知障碍的住院养老院居民,治疗模式激进的医院并未提高生存率。

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本文引用的文献

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Decision-making and outcomes of feeding tube insertion: a five-state study.喂养管插入的决策和结果:一项五州研究。
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Aggressive treatment style and surgical outcomes.激进的治疗方式和手术结果。
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Hospital characteristics associated with feeding tube placement in nursing home residents with advanced cognitive impairment.与高级认知障碍的养老院居民置管相关的医院特征。
JAMA. 2010 Feb 10;303(6):544-50. doi: 10.1001/jama.2010.79.
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Looking forward, looking back: assessing variations in hospital resource use and outcomes for elderly patients with heart failure.展望未来,回顾过去:评估老年心力衰竭患者医院资源使用及治疗结果的差异
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Natural history of feeding-tube use in nursing home residents with advanced dementia.晚期痴呆养老院居民使用饲管的自然病程。
J Am Med Dir Assoc. 2009 May;10(4):264-70. doi: 10.1016/j.jamda.2008.10.010. Epub 2009 Jan 9.
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Enteral tube feeding for older people with advanced dementia.为患有晚期痴呆症的老年人提供肠内管饲。
Cochrane Database Syst Rev. 2009 Apr 15;2009(2):CD007209. doi: 10.1002/14651858.CD007209.pub2.
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Dementia and cognitive impairment are not associated with earlier mortality after percutaneous endoscopic gastrostomy.经皮内镜下胃造口术后,痴呆和认知障碍与较早死亡率无关。
JPEN J Parenter Enteral Nutr. 2009 Jan-Feb;33(1):62-6. doi: 10.1177/0148607108321709. Epub 2008 Sep 30.
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