MyoD1 基因内含子 2 中的 SNP 与三个鸭群体的生长和胴体性状相关。

An SNP in the MyoD1 gene intron 2 associated with growth and carcass traits in three duck populations.

机构信息

Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Science, Wuhan, 430064, China.

出版信息

Biochem Genet. 2012 Dec;50(11-12):898-907. doi: 10.1007/s10528-012-9530-4. Epub 2012 Aug 8.

Abstract

Myogenic differentiation 1 (MyoD1) genes belong to the MyoD gene family and play key roles in growth and muscle development. This study was designed to investigate the effects of variants in the MyoD1 gene on duck growth and carcass traits. Three duck populations (Cherry Valley, Jingjiang, and Muscovy) were sampled, their growth and carcass traits were measured, and they were genotyped using the PCR-RFLP method. The results showed one novel polymorphism, an alteration in intron 2 of the MyoD1 gene (A to T). It was associated with the traits of weight at 8 weeks, carcass weight, breast muscle weight, leg muscle weight, eviscerated percentage, percentage of leg muscle weight, dressing percentage, and lean meat percentage. This alteration in intron 2 of MyoD1 may be linked with potential major loci or genes affecting some growth and carcass traits.

摘要

肌源性分化 1（MyoD1）基因属于 MyoD 基因家族，在生长和肌肉发育中发挥着关键作用。本研究旨在探讨 MyoD1 基因变异对鸭生长和胴体性状的影响。本研究对樱桃谷鸭、京江黄鸡和瘤头鸭三个鸭群体进行了采样，使用 PCR-RFLP 方法对其进行了生长和胴体性状的测量和基因型分析。结果表明，MyoD1 基因的内含子 2 发生了一个新的多态性（A 到 T 的改变）。该多态性与 8 周龄体重、胴体重、胸肌重、腿肌重、屠体净膛率、腿肌重百分比、屠体出肉率和瘦肉率有关。MyoD1 内含子 2 的这种改变可能与潜在的影响某些生长和胴体性状的主要基因座或基因有关。