电离辐射会影响阿尔茨海默病的发病风险吗？
Does ionizing radiation influence Alzheimer's disease risk?
机构信息
Center for Nuclear Medicine and Ultrasound, Rajshahi Medical College Hospital Campus, GPO Box No. 35, Rajshahi, Bangladesh.
出版信息
J Radiat Res. 2012 Nov 1;53(6):815-22. doi: 10.1093/jrr/rrs036. Epub 2012 Aug 7.
Abstract
Alzheimer's disease (AD) is a human neurodegenerative disease, and its global prevalence is predicted to increase dramatically in the following decades. There is mounting evidence describing the effects of ionizing radiation (IR) on the brain, suggesting that exposure to IR might ultimately favor the development of AD. Therefore better understanding the possible connections between exposure to IR and AD pathogenesis is of utmost importance. In this review, recent developments in the research on the biological and cognitive effects of IR in the brain will be explored. Because AD is largely an age-related pathology, the effects of IR on ageing will be investigated.
摘要
阿尔茨海默病（AD）是一种人类神经退行性疾病，预计在未来几十年内其全球患病率将大幅上升。越来越多的证据描述了电离辐射（IR）对大脑的影响，表明接触 IR 可能最终有利于 AD 的发展。因此，更好地了解接触 IR 与 AD 发病机制之间的可能联系至关重要。在这篇综述中，将探讨 IR 对大脑的生物学和认知影响的研究的最新进展。由于 AD 主要是一种与年龄相关的疾病，因此将研究 IR 对衰老的影响。
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