[A comparative evaluation of oral and parenteral cephalosporins in inhibiting the growth of bacteria pathogenic to the periodontium].

A study was carried out in vitro to assess the inhibitory activity on the growth of Bacteroides gingivalis and Bacteroides intermedius using two oral cephalosporins (Cephalexin and Cephradine) in comparison to two parenteral cephalosporins (Cefotaxime and Ceftriaxon) and the classic Tetracycline HCl. The results of the study show that the inhibitory activity on the growth of the two periodontopathogenic bacteria produced by the oral cephalosporins is comparable to that of other antibiotics studied, and that in comparison to parenteral cephalosporins the former have the advantage of being better accepted and more economic.