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超声引导下宫颈环扎术:希罗德卡尔术式与麦克唐纳术式对比

Ultrasound-indicated cerclage: Shirodkar vs. McDonald.

作者信息

Hume Heather, Rebarber Andrei, Saltzman Daniel H, Roman Ashley S, Fox Nathan S

机构信息

Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York University School of Medicine, New York, NY, USA.

出版信息

J Matern Fetal Neonatal Med. 2012 Dec;25(12):2690-2. doi: 10.3109/14767058.2012.716465. Epub 2012 Aug 21.

Abstract

OBJECTIVE

To compare the efficacy of Shirodkar to McDonald cerclage in patients with singleton pregnancies undergoing an ultrasound-indicated cerclage.

METHODS

Historical cohort of all patients with singleton pregnancies undergoing cerclage for the indication of a short cervix on ultrasound (ultrasound indicated) at one institution in 2005-2010. We compared outcomes based on cerclage type, Shirodkar or McDonald. Outcome measures were gestational age (GA) at delivery, delivery ≥35 weeks, ≥32 weeks, and PPROM. Multivariable regression analysis was performed to control for significant variables.

RESULTS

Seventy-four patients with singleton pregnancies underwent an ultrasound-indicated cerclage in the study period (47 Shirodkar, 27 McDonald). Shirodkar was associated with later GA at delivery (mean GA at delivery 36.98 +/- 3.39 vs. 33.34 +/- 6.37 weeks, p = 0.006), a higher likelihood of delivering ≥35 weeks (83 vs. 55.6%, p = 0.011) and ≥32 weeks (91.5 vs. 59.3%, p = 0.001), and a lower likelihood of preterm premature rupture of membrane (PPROM) (13.0 vs. 46.2%, p = 0.002). On adjusted analysis controlling for differing baseline characteristics, Shirodkar remained significantly associated with an increased incidence of delivery ≥32 weeks (odds ratio [OR]: 5.180, 95% CI: 1.024-26.205).

CONCLUSION

Compared to the McDonald technique, the Shirodkar technique was more effective in prolonging pregnancy in patients with singleton pregnancies undergoing ultrasound-indicated cerclage. A prospective trial is needed to compare these two techniques.

摘要

目的

比较希罗德卡尔(Shirodkar)宫颈环扎术与麦克唐纳(McDonald)宫颈环扎术对单胎妊娠且超声提示需行宫颈环扎术患者的疗效。

方法

对2005年至2010年在某一机构因超声提示宫颈短而接受宫颈环扎术的所有单胎妊娠患者进行回顾性队列研究。我们根据宫颈环扎术类型(希罗德卡尔或麦克唐纳)比较结局。结局指标为分娩时的孕周(GA)、孕周≥35周分娩、≥32周分娩以及未足月胎膜早破(PPROM)。进行多变量回归分析以控制显著变量。

结果

在研究期间,74名单胎妊娠患者接受了超声提示的宫颈环扎术(47例行希罗德卡尔宫颈环扎术,27例行麦克唐纳宫颈环扎术)。希罗德卡尔宫颈环扎术与分娩时孕周较晚相关(分娩时平均孕周36.98±3.39周 vs. 33.34±6.37周,p = 0.006),孕周≥35周分娩的可能性更高(83% vs. 55.6%,p = 0.011)以及孕周≥32周分娩的可能性更高(91.5% vs. 59.3%,p = 0.001),且未足月胎膜早破的可能性更低(13.0% vs. 46.2%,p = 0.002)。在对不同基线特征进行校正分析时,希罗德卡尔宫颈环扎术仍与孕周≥32周分娩的发生率增加显著相关(优势比[OR]:5.180,95%置信区间:1.024 - 26.205)。

结论

与麦克唐纳技术相比,希罗德卡尔技术在延长单胎妊娠且超声提示需行宫颈环扎术患者的孕周方面更有效。需要进行前瞻性试验来比较这两种技术。

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