Ventolini G, Genrich T J, Roth J, Neiger R
Department of Obstetrics and Gynecology, Wright State University Boonshoft School of Medicine, Dayton, OH 45409, USA.
J Perinatol. 2009 Apr;29(4):276-9. doi: 10.1038/jp.2008.221. Epub 2009 Jan 22.
OBJECTIVE: Mid-trimester painless cervical dilation is associated with high rates of perinatal morbidity and mortality. 'Rescue' cerclage is one option in managing these patients. We evaluated pregnancy outcomes of women in whom we placed Shirodkar cerclage. STUDY DESIGN: We analyzed the pregnancy outcome of a retrospective cohort of women carrying singleton pregnancies who experienced late mid-trimester cervical dilation in whom we placed Shirodkar cerclage. Exclusion criteria were uterine contractions, bleeding, premature rupture of membranes and chorioamnionitis. Primary outcomes were gestational age at delivery, maternal, fetal and neonatal outcomes and surgical complications. RESULT: Between January 2003 and December 2005, 68 patients met our inclusion criteria. The average maternal age was 26.4+/-8.3 years and the mean gestational age at the time of surgery was 19.6+/-3.2 weeks. Seven women opted for expectant management and 5 more were followed up by their referring physicians; the 12 of them were used as a comparison group. Fifty-six women underwent placement of Shirodkar cerclage. We were unable to place a cerclage in three women (5.1%) and all three delivered before 23 weeks. Of the 56 women who had cerclage, 14 (23.7%) delivered at term, 20 (33.9%) delivered between 34 and 36.9 weeks, 13 (22%) between 30 and 33.9 weeks, 6 (10.2%) between 24 and 29.9 weeks and 3 (5.1%) before 24 weeks. Median time from diagnosis to delivery was longer in the cerclage group (9.1 weeks) than in the comparison group (3.3 weeks P<0.01). CONCLUSION: When pregnancies are complicated by late mid-trimester cervical dilation, placement of Shirodkar cerclage in appropriately selected patients has the potential to be a beneficial therapeutic option.
目的:孕中期无痛宫颈扩张与围产期高发病率和死亡率相关。“补救性”宫颈环扎术是处理这些患者的一种选择。我们评估了接受希罗德卡尔宫颈环扎术的女性的妊娠结局。 研究设计:我们分析了一组单胎妊娠女性的回顾性队列的妊娠结局,这些女性在孕中期晚期出现宫颈扩张并接受了希罗德卡尔宫颈环扎术。排除标准为子宫收缩、出血、胎膜早破和绒毛膜羊膜炎。主要结局为分娩时的孕周、母体、胎儿和新生儿结局以及手术并发症。 结果:2003年1月至2005年12月期间,68例患者符合我们的纳入标准。产妇平均年龄为26.4±8.3岁,手术时的平均孕周为19.6±3.2周。7名女性选择期待治疗,另有5名由转诊医生进行随访;将这12名女性作为对照组。56名女性接受了希罗德卡尔宫颈环扎术。3名女性(5.1%)无法进行环扎术,且这3名女性均在23周前分娩。在接受环扎术的56名女性中,14名(23.7%)足月分娩,20名(33.9%)在34至36.9周之间分娩,13名(22%)在30至33.9周之间分娩,6名(10.2%)在24至29.9周之间分娩,3名(5.1%)在24周前分娩。环扎术组从诊断到分娩的中位时间(9.1周)长于对照组(3.3周,P<0.01)。 结论:当妊娠合并孕中期晚期宫颈扩张时,在适当选择的患者中进行希罗德卡尔宫颈环扎术有可能成为一种有益的治疗选择。
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