超声评估早期胚胎形态及其与难免流产卵黄囊的相关性。

Early embryonic morphology sonographically assessed and its correlation with yolk sac in missed abortion.

机构信息

Departamento de Obstetricia y Ginecología, Facultad de Medicina, Universidad de Granada, Avda. Madrid s/n, 18014 Granada, Spain.

出版信息

Arch Gynecol Obstet. 2013 Jan;287(1):139-42. doi: 10.1007/s00404-012-2499-8. Epub 2012 Aug 9.

DOI:10.1007/s00404-012-2499-8

PMID:22875048

Abstract

PURPOSE

To provide additional information about embryo morphology sonographic assessment and its correlation with yolk sac.

METHODS

A systematic study in 200 consecutive cases of missed abortion <10 weeks diagnosed by transvaginal ultrasound.

RESULTS

In 104 gestations of embryos with morphological abnormalities, 88 (84.6 %) were at least 1 week smaller than expected for gestational age and 16 (15.4 %) were the expected size. From 32 normal morphologic embryos, 7 (21.9 %) were at least 1 week smaller than expected for gestational age, and 25 (78.1 %) were the expected size (p < 0.005). Normal morphologic embryos are linked more frequently with normal yolk sac (62.5 %). Findings in anembryonic gestations (GD1) included an absent yolk sac (46.9 %) and a cystic yolk sac (25 %). Likewise, findings in GD2-3 embryos included more frequently a cystic yolk sac (42.9 %) and an absent yolk sac (32.5 %). GD4 embryos are associated with an echogenic yolk sac (40 %), a relatively small-hypoplastic- (40 %) and a relatively large-cystic- (20 %). In DI embryos, yolk sac appears cystic (62.5 %) or echogenic (37.5 %).

CONCLUSIONS

Our study proves the correlation between morphology of conceptuses and yolk sac appearance in cases of missed abortion.

摘要

目的

提供胚胎形态超声评估及其与卵黄囊相关性的更多信息。

方法

对 200 例经阴道超声诊断为 10 周内难免流产的连续病例进行系统研究。

结果

在 104 例形态异常的胚胎妊娠中，88 例（84.6%）至少比预期孕周小 1 周，16 例（15.4%）与预期大小相符。在 32 例形态正常的胚胎中，7 例（21.9%）至少比预期孕周小 1 周，25 例（78.1%）与预期大小相符（p<0.005）。形态正常的胚胎与正常卵黄囊更频繁相关（62.5%）。无胚胎妊娠（GD1）的发现包括卵黄囊缺失（46.9%）和囊性卵黄囊（25%）。同样，GD2-3 胚胎的发现更频繁地出现囊性卵黄囊（42.9%）和卵黄囊缺失（32.5%）。GD4 胚胎与回声卵黄囊（40%）、相对小的发育不良卵黄囊（40%）和相对大的囊性卵黄囊（20%）相关。在 DI 胚胎中，卵黄囊呈囊性（62.5%）或回声增强（37.5%）。