Okazaki Tadaharu, Nishimura Kinya, Koga Hiroyuki, Miyano Go, Okawada Manabu, Shoji Hiromichi, Shimizu Toshiaki, Makino Shintaro, Takeda Satoru, Inada Eiichi, Lane Geoffrey J, Yamataka Atsuyuki
Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Pediatr Surg Int. 2012 Sep;28(9):883-6. doi: 10.1007/s00383-012-3148-9.
We reviewed 24 consecutive cases of prenatally or immediately postnatally diagnosed left-sided congenital diaphragmatic hernia (CDH) to evaluate pulmonary artery (PA) size as an indication for thoracoscopic repair (TR).
CDH repair is planned once echocardiography confirms improvement in pulmonary hypertension. TR is chosen if cardiopulmonary status is stable more than 10 min in the decubitus position in the neonatal intensive care unit (NICU) under conventional mechanical or high frequency oscillatory ventilation (HFOV) with/without nitric oxide (NO) and the patient appears likely to tolerate manual ventilation during transfer to the operating room. Otherwise open repair (OR) is performed in NICU. Proximal right PA (RPA) and left PA (LPA) diameters measured at birth were assessed with respect to the type of repair.
10/24 had TR and 14/24 had OR. TR cases had significantly larger RPA/LPA diameters (3.52 ± 0.23 vs. 3.10 ± 0.56 mm, p < 0.05 for RPA; 3.04 ± 0.26 vs. 2.48 ± 0.37, p < 0.01 for LPA), and significantly less requirement for HFOV (70 vs. 100 %, p < 0.05) and NO (20 vs. 86 %, p < 0.01). Four TR required conversion to OR for technical reasons (n = 3) and cardiopulmonary instability (n = 1).
TR can be considered when RPA/LPA diameters are larger than 3.0/2.5 mm, respectively, and cardiopulmonary status is stable without NO.
我们回顾了24例产前或产后立即诊断为左侧先天性膈疝(CDH)的连续病例,以评估肺动脉(PA)大小作为胸腔镜修复(TR)指征的情况。
一旦超声心动图证实肺动脉高压有所改善,即计划进行CDH修复。如果在新生儿重症监护病房(NICU)中,患者在常规机械通气或高频振荡通气(HFOV)下,无论有无一氧化氮(NO),在侧卧位时心肺状态稳定超过10分钟,且在转运至手术室期间似乎能够耐受手动通气,则选择TR。否则在NICU进行开放修复(OR)。根据修复类型评估出生时测量的右肺动脉(RPA)和左肺动脉(LPA)近端直径。
24例中10例行TR,14例行OR。TR病例的RPA/LPA直径明显更大(RPA:3.52±0.23对3.10±0.56mm,p<0.05;LPA:3.04±0.26对2.48±0.37,p<0.01),对HFOV(70%对100%,p<0.05)和NO(20%对86%,p<0.01)的需求明显更少。4例TR因技术原因(n=3)和心肺不稳定(n=1)需要转为OR。
当RPA/LPA直径分别大于3.0/2.5mm且心肺状态稳定且无需NO时,可以考虑TR。