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先天性膈疝的微创修复。

Minimally invasive repair of congenital diaphragmatic hernia.

机构信息

Department of Pediatric Surgery, The University of Texas School of Medicine at Houston, Houston, TX 77030, USA.

出版信息

J Pediatr Surg. 2011 Jun;46(6):1158-64. doi: 10.1016/j.jpedsurg.2011.03.050.

Abstract

PURPOSE

Operative approach, including minimally invasive surgery (MIS) in the repair of congenital diaphragmatic hernia (CDH), is variable among institutions. The short-term recurrent hernia rate is not well described. We evaluated the in-hospital recurrence rate of MIS repairs of infants with CDH from the Congenital Diaphragmatic Hernia Registry.

METHODS

Prospectively collected data from infants with CDH were analyzed from the Congenital Diaphragmatic Hernia Registry from January 1995 to January 2010. Recurrent hernia was defined as reoperations during initial hospitalization. Operative approaches included abdominal, thoracic, laparoscopic, and thoracoscopic techniques.

RESULTS

Five thousand four hundred eighty infants with CDH were identified, of which 4516 (82.4%) were repaired. Operative data were available in 4390 infants. One hundred fifty-one infants (3.4%) underwent MIS repairs with 12 reported recurrences (7.9%) compared with 114 for open techniques (2.7%, P < .05). Minimally invasive surgery demonstrated a significant increased odds for recurrence (odds ratio, 3.59; 95% confidence interval, 1.92-6.71) after adjusting for gestational age, birth weight, patch repair, and extracorporeal membrane oxygenation.

CONCLUSION

Minimally invasive techniques appear to have a significant higher recurrent hernia rate, with thoracoscopy being the highest. Although adjusted for patch repair, other factors with regard to disease severity may contribute to differences in outcomes among centers. This study is limited to short-term recurrence during initial hospitalization.

摘要

目的

先天性膈疝(CDH)的手术方法包括微创手术(MIS),但各机构的方法存在差异。目前尚未很好地描述短期复发疝的发生率。我们评估了先天性膈疝登记处中婴儿 CDH 经 MIS 修复后的住院内复发率。

方法

从 1995 年 1 月至 2010 年 1 月,前瞻性地收集先天性膈疝登记处中婴儿 CDH 的资料。将复发疝定义为初始住院期间的再次手术。手术方法包括腹部、胸部、腹腔镜和胸腔镜技术。

结果

共确定了 5480 例患有 CDH 的婴儿,其中 4516 例(82.4%)接受了修复。在 4390 例婴儿中有手术资料。151 例婴儿(3.4%)接受了 MIS 修复,其中 12 例(7.9%)报告复发,而开放技术的 114 例(2.7%)为复发(P <.05)。调整胎龄、出生体重、补片修补和体外膜肺氧合后,MIS 显示出复发的几率明显增加(比值比,3.59;95%置信区间,1.92-6.71)。

结论

微创技术似乎具有更高的复发疝率,其中胸腔镜的复发率最高。尽管调整了补片修补,但与疾病严重程度相关的其他因素可能导致各中心之间的结果存在差异。本研究仅限于初始住院期间的短期复发。

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