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[髓脑脊髓炎患者脑脊液中溶菌酶水平测定的价值评估]

[Evaluation of the value of determining lysozyme levels in cerebrospinal fluid in myeloencephalitis].

作者信息

Miczek J

机构信息

I Katedry i Kliniki Chorób Zakaźnych Sl. AM w Bytomiu.

出版信息

Pol Tyg Lek. 1990;45(27-28):553-6.

PMID:2287577
Abstract

The study aimed at assessing the value lysozyme assay in CFS as indicator of the damage to blood-cerebrospinal fluid barrier and intensification of inflammatory process in the course of meningitis. The study involved 20 patients with suppurative and 66 with viral meningitis. Control group included 26 patients without nervous system disease. To estimate the degree of blood-cerebrospinal fluid barrier damage albumin and lysozyme indicators were calculated. It was proved, that CSF lysozyme levels are bigger in the suppurative meningitis than in viral meningitis. According to the author, CSF lysozyme levels the value of lysozyme indicator may inform on intensification of the inflammatory process and the degree of blood-cerebrospinal fluid barrier damage in suppurative meningitis, whereas in the viral meningitis they inform on degree of blood-cerebrospinal fluid barrier damage, only.

摘要

该研究旨在评估溶菌酶检测在慢性疲劳综合征(CFS)中作为血脑脊髓液屏障损伤及脑膜炎病程中炎症过程加剧指标的价值。该研究纳入了20例化脓性脑膜炎患者和66例病毒性脑膜炎患者。对照组包括26例无神经系统疾病的患者。为评估血脑脊髓液屏障损伤程度,计算了白蛋白和溶菌酶指标。结果证明,化脓性脑膜炎患者脑脊液中溶菌酶水平高于病毒性脑膜炎患者。作者认为,脑脊液溶菌酶水平即溶菌酶指标的值可反映化脓性脑膜炎中炎症过程的加剧及血脑脊髓液屏障损伤程度,而在病毒性脑膜炎中仅反映血脑脊髓液屏障损伤程度。

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