Moonis Gul, Cunnane Mary Beth, Emerick Kevin, Curtin Hugh
Department of Radiology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA.
Magn Reson Imaging Clin N Am. 2012 Aug;20(3):435-46. doi: 10.1016/j.mric.2012.05.006. Epub 2012 Jun 15.
Perineural tumor spread (PNS) is a mode of neoplastic spread whereby tumor cells use neural conduits to escape the borders of a primary tumor. MRI is generally favored over CT for evaluating PNS, and findings include obliteration of fat within skull base foramina, enlargement and enhancement of the involved nerves, and enlargement and destruction of the bony foramina. Careful examination of the entire course of the nerve allows detection of skip lesions. Recognition of the complete extent of PNS is crucial for correct treatment because it facilitates both surgical and radiotherapy targeting of entire extent of disease.
神经周围肿瘤扩散（PNS）是一种肿瘤扩散方式，肿瘤细胞通过神经管道逃离原发肿瘤边界。在评估PNS方面，MRI通常比CT更受青睐，其表现包括颅底孔内脂肪消失、受累神经增粗和强化以及骨孔扩大和破坏。仔细检查神经的全程有助于发现跳跃性病变。认识PNS的完整范围对于正确治疗至关重要，因为这有利于针对疾病的整个范围进行手术和放疗。
