• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

母婴双相障碍对高危后代的影响:一项关于计划生育和母婴护理的对照研究。

Burden of maternal bipolar disorder on at-risk offspring: a controlled study on family planning and maternal care.

机构信息

Mood Disorders Unit, Department and Institute of Psychiatry, Clinical Hospital, School of Medicine, University of Sao Paulo, Brazil.

出版信息

J Affect Disord. 2012 Dec 20;143(1-3):172-8. doi: 10.1016/j.jad.2012.05.050. Epub 2012 Aug 9.

DOI:10.1016/j.jad.2012.05.050
PMID:22877968
Abstract

INTRODUCTION

Bipolar disorder (BD) is a highly incapacitating disease typically associated with high rates of familial dysfunction. Despite recent literature suggesting that maternal care is an important environmental factor in the development of behavioral disorders, it is unclear how much maternal care is dysfunctional in BD subjects.

OBJECTIVE

The objective of this study was to characterize maternal care in DSM-IV/SCID diagnosed BD type I subjects compared to healthy controls with (PD) and without (NPD) other psychiatric diagnoses.

MATERIALS AND METHODS

Thirty-four BD mothers and 106 controls underwent an interview about family planning and maternal care, obstetrical complications, and mother-child interactions. K-SADS-PL questions about violence exposure were used to ascertain domestic violence and physical/sexual abuse.

RESULTS

BD mothers were less likely to have stable unions (45.5%; p<0.01) or to live with the biological father of their children (33.3%; p<0.01), but had higher educational level and higher rates of social security use/retirement. They also had fewer children and used less contraceptive methods than controls. Children of BD women had higher rates of neonatal anoxia, and reported more physical abuse (16.1%; p=0.02) than offspring of NPD mothers. Due to BD mothers' symptoms, 33.3% of offspring suffered physical and/or psychological abuse.

LIMITATIONS

Post hoc analysis, and the use of questions as a surrogate of symptoms as opposed to validated instruments.

CONCLUSION

This is one of few reports confirming that maternal care given by BD women is dysfunctional. BD psychopathology can lead to poor maternal care and both should be considered important environmental risk factors in BD, suggesting that BD psychoeducation should include maternal care orientation.

摘要

简介

双相情感障碍(BD)是一种高度致残的疾病,通常与家庭功能障碍的高发生率有关。尽管最近的文献表明,母性关怀是行为障碍发展的一个重要环境因素,但BD 患者的母性关怀有多少是功能失调的还不清楚。

目的

本研究的目的是比较 DSM-IV/SCID 诊断的 BD 型 I 患者与有(PD)和无(NPD)其他精神诊断的健康对照者的母性关怀特征。

材料和方法

34 名 BD 母亲和 106 名对照者接受了关于家庭计划和母性关怀、产科并发症和母婴互动的访谈。K-SADS-PL 关于暴力暴露的问题用于确定家庭暴力和身体/性虐待。

结果

BD 母亲更不可能有稳定的婚姻(45.5%;p<0.01)或与孩子的生父一起生活(33.3%;p<0.01),但她们的教育程度更高,社会安全使用/退休的比例更高。她们的孩子也更少,使用的避孕方法也比对照组少。BD 女性的孩子有更高的新生儿缺氧率,并报告了更多的身体虐待(16.1%;p=0.02),比 NPD 母亲的孩子多。由于 BD 母亲的症状,33.3%的子女遭受身体和/或心理虐待。

局限性

事后分析,以及使用问题作为症状的替代物,而不是使用经过验证的工具。

结论

这是少数几个证实 BD 女性提供的母性关怀是功能失调的报告之一。BD 精神病理学可导致母性关怀不良,两者都应被视为 BD 的重要环境风险因素,这表明 BD 心理教育应包括母性关怀指导。

相似文献

1
Burden of maternal bipolar disorder on at-risk offspring: a controlled study on family planning and maternal care.母婴双相障碍对高危后代的影响:一项关于计划生育和母婴护理的对照研究。
J Affect Disord. 2012 Dec 20;143(1-3):172-8. doi: 10.1016/j.jad.2012.05.050. Epub 2012 Aug 9.
2
Type and timing of mothers' victimization: effects on mothers and children.母亲受侵害的类型与时机:对母亲和儿童的影响
Pediatrics. 2001 Apr;107(4):728-35. doi: 10.1542/peds.107.4.728.
3
The impact of childhood abuse history, domestic violence and mental health symptoms on parenting behaviour among mothers in Japan.童年虐待史、家庭暴力和心理健康症状对日本母亲养育行为的影响。
Child Care Health Dev. 2012 Jul;38(4):530-7. doi: 10.1111/j.1365-2214.2011.01272.x. Epub 2011 Jun 22.
4
Dysfunctional family environment in affected versus unaffected offspring of parents with bipolar disorder.双相障碍父母的患病子女与未患病子女的功能失调家庭环境。
Aust N Z J Psychiatry. 2013 Nov;47(11):1051-7. doi: 10.1177/0004867413506754. Epub 2013 Oct 9.
5
The early manifestations of bipolar disorder: a longitudinal prospective study of the offspring of bipolar parents.双相情感障碍的早期表现:一项对双相情感障碍患者后代的纵向前瞻性研究。
Bipolar Disord. 2007 Dec;9(8):828-38. doi: 10.1111/j.1399-5618.2007.00421.x.
6
Psychiatric Disorders and Quality of Life in the Offspring of Parents with Bipolar Disorder.双相情感障碍患者后代的精神疾病与生活质量
J Child Adolesc Psychopharmacol. 2017 Aug;27(6):483-493. doi: 10.1089/cap.2016.0056. Epub 2017 Jun 5.
7
Childhood adversity, parental vulnerability and disorder: examining inter-generational transmission of risk.童年逆境、父母的脆弱性与疾病:探究风险的代际传递。
J Child Psychol Psychiatry. 2002 Nov;43(8):1075-86. doi: 10.1111/1469-7610.00234.
8
Early risk factors for psychopathology in offspring of parents with bipolar disorder: the role of obstetric complications and maternal comorbid anxiety.双相情感障碍患者后代精神病理学的早期风险因素:产科并发症和母亲共病焦虑的作用。
Depress Anxiety. 2014 Jul;31(7):583-90. doi: 10.1002/da.22254. Epub 2014 Mar 18.
9
Children of depressed mothers 1 year after the initiation of maternal treatment: findings from the STAR*D-Child Study.母亲开始治疗1年后抑郁母亲的子女:STAR*D-儿童研究的结果。
Am J Psychiatry. 2008 Sep;165(9):1136-47. doi: 10.1176/appi.ajp.2008.07081286. Epub 2008 Jun 16.
10
Role of maternal childhood trauma on parenting among depressed mothers of psychiatrically ill children.母亲童年创伤对精神病患儿抑郁母亲养育方式的影响。
Depress Anxiety. 2013 Sep;30(9):792-9. doi: 10.1002/da.22116. Epub 2013 May 3.

引用本文的文献

1
Offspring of mothers with bipolar disorder: a systematic review considering personality features.患有双相情感障碍的母亲的后代:一项考虑人格特征的系统评价。
Braz J Psychiatry. 2022 Jan-Feb;44(1):94-102. doi: 10.1590/1516-4446-2020-1465.
2
Disrespect and abuse as a predictor of postnatal care utilisation and maternal-newborn well-being: a mixed-methods systematic review.不尊重和虐待作为产后护理利用和母婴健康的预测因素:一项混合方法系统评价。
BMJ Glob Health. 2021 Apr;6(4). doi: 10.1136/bmjgh-2020-004698.
3
Psychiatric disorders among offspring of patients with Bipolar and Borderline Personality Disorder.
双相及边缘型人格障碍患者后代的精神障碍。
J Clin Psychol. 2019 Oct;75(10):1810-1819. doi: 10.1002/jclp.22817. Epub 2019 Jun 10.
4
Interparental violence and maternal mood disorders as predictors of adolescent physical aggression within the family.父母间暴力和母亲情绪障碍作为家庭中青少年身体攻击行为的预测因素。
Aggress Behav. 2015 May;41(3):253-66. doi: 10.1002/ab.21569.
5
Categorical and dimensional psychopathology in Dutch and US offspring of parents with bipolar disorder: A preliminary cross-national comparison.荷兰和美国双相情感障碍患者后代的分类与维度精神病理学:一项初步的跨国比较。
J Affect Disord. 2016 Nov 15;205:95-102. doi: 10.1016/j.jad.2016.06.011. Epub 2016 Jun 11.
6
Maternal-Infant interaction in women with unipoloar and bipolar depression.单相和双相抑郁症女性的母婴互动
Appl Nurs Res. 2015 Nov;28(4):381-3. doi: 10.1016/j.apnr.2015.01.012. Epub 2015 Feb 26.
7
Association of Anxiety Symptoms in Offspring of Bipolar Parents with Serotonin Transporter-Linked Polymorphic Region (5-HTTLPR) Genotype.双相情感障碍患者后代的焦虑症状与血清素转运体相关多态性区域(5-HTTLPR)基因型的关联
J Child Adolesc Psychopharmacol. 2015 Aug;25(6):458-66. doi: 10.1089/cap.2014.0115. Epub 2015 Jul 28.
8
Dimensional psychopathology in preschool offspring of parents with bipolar disorder.双相障碍父母学龄前子女的多维精神病理学。
J Child Psychol Psychiatry. 2014;55(2):144-53. doi: 10.1111/jcpp.12137. Epub 2013 Dec 30.