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充血性心力衰竭中的锌与铜

Zinc and copper in congestive heart failure.

作者信息

Atlihan F, Söylemezoğlu T, Gökçe A, Güvendik G, Satici O

机构信息

Department of Pediatrics, Dicle University Faculty of Medicine, Diyarbakir.

出版信息

Turk J Pediatr. 1990 Jan-Mar;32(1):33-8.

PMID:2288016
Abstract

In this study serum zinc (Zn) and copper (Cu) levels in children with congestive heart failure (CHF) were evaluated. The mean serum Zn levels of the patients with CHF were 92.9 +/- 18.9 micrograms/100 ml, and they showed a significant decrease when compared to controls (p less than 0.05). The mean serum Cu levels, which were 173.6 +/- 26.6 micrograms/100 ml, showed a significant increase when compared to controls (p less than 0.001). After digoxin therapy, a significant increase in Zn levels and a significant decrease in Cu levels were observed.

摘要

本研究评估了充血性心力衰竭(CHF)患儿的血清锌(Zn)和铜(Cu)水平。CHF患儿的血清锌平均水平为92.9±18.9微克/100毫升,与对照组相比显著降低(p<0.05)。血清铜平均水平为173.6±26.6微克/100毫升,与对照组相比显著升高(p<0.001)。地高辛治疗后,观察到锌水平显著升高,铜水平显著降低。

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引用本文的文献

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Cardiovasc Toxicol. 2025 Sep 23. doi: 10.1007/s12012-025-10063-x.
2
Role of copper homeostasis and cuproptosis in heart failure pathogenesis: implications for therapeutic strategies.铜稳态和铜死亡在心力衰竭发病机制中的作用:对治疗策略的启示。
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Association between biomarkers of zinc and copper status and heart failure: a meta-analysis.
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ESC Heart Fail. 2024 Oct;11(5):2546-2556. doi: 10.1002/ehf2.14837. Epub 2024 May 1.
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Cardiovascular Diseases and Zinc.心血管疾病与锌
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The Relationship between Serum Zinc Level and Heart Failure: A Meta-Analysis.血清锌水平与心力衰竭的关系:一项荟萃分析。
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Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.锌缺乏在某些疾病发病机制中的生物学后果。
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