Bednova V N, Amantaev N B, Timchenko G F, Babiĭ A V, Viktorova G A
Vestn Dermatol Venerol. 1990(11):42-6.
A total of 156 patients with early syphilis were treated with tetracyclin and oletetrin. The drugs were administered 4 times daily (every 6 hrs) in a dose of 0.5 g (daily dose 2.0 g). Patients with primary seropositive syphilis were treated for 20 days, the dose per course being 40 g, those with secondary fresh syphilis for 25 days, dose per course 50 g, those with secondary recurring syphilis for 40 days, dose per course 80 g. The treatment was well tolerated by all the patients. Early negative results of specific serologic tests after treatment confirm the efficacy of the suggested method.
总共156例早期梅毒患者接受了四环素和油酸四环素治疗。药物每日给药4次(每6小时一次),剂量为0.5克(每日剂量2.0克)。一期血清阳性梅毒患者治疗20天,每疗程剂量为40克;二期初发性梅毒患者治疗25天,每疗程剂量50克;二期复发性梅毒患者治疗40天,每疗程剂量80克。所有患者对该治疗耐受性良好。治疗后特异性血清学检测的早期阴性结果证实了所建议方法的有效性。