Maxillo-Facial Surgery Operative Unit, Head and Neck Department, University-Hospital of Parma, Via Gramsci 14, 43100 Parma (Pr), Italy.
J Craniomaxillofac Surg. 2013 Mar;41(2):167-71. doi: 10.1016/j.jcms.2012.07.005. Epub 2012 Aug 9.
Free flaps represent the first reconstructive option for many head and neck defects. The increasing life expectancy of the population results in increasing numbers of ageing patients facing complex reconstructive surgery. In this study we evaluated our experience with free-flap transfers in older patients, analysing the post-operative reconstructive and systemic complications.
Between 2000 and 2009, 360 patients underwent free flap reconstruction of defects resulting from the treatment of head and neck tumours at the Operative Unit of Maxillofacial Surgery, University - Hospital of Parma, Italy. Fifty-five patients (15.3%) were more than 75 years old at the time of treatment.
At the end of the follow-up successful free-flap transfer was achieved in 360 of the 373 flaps harvested (96.5%). The overall reconstructive complication rate was 31.4%, (31.8% in the younger group and 29.1% in the remaining patients). Medical complications were observed in 29.2% of cases (less than 75 years: 28.8%; more than 75 years: 30.9%). The ASA status was associated with a statistically significantly higher incidence of complications within patients less than 75 years old (p < 0.0001).
The results of this study, in agreement with previous studies, provide evidence that free-tissue transfer may be performed in ageing patients with a high degree of technical success. The chronologic age cannot be considered an appropriate criterion in the reconstructive decision. On the contrary, a careful selection of the patients based on comorbidities and general conditions (ASA status) is of primary importance in reducing post-operative complications and to improving the results of surgery.
游离皮瓣是许多头颈部缺损的首选重建方法。人口预期寿命的延长导致越来越多的老年患者面临复杂的重建手术。在这项研究中,我们评估了我们在老年患者中使用游离皮瓣转移的经验,分析了术后重建和全身并发症。
2000 年至 2009 年间,意大利帕尔马大学附属医院颌面外科手术部对 360 例头颈部肿瘤治疗后缺损的患者进行了游离皮瓣重建。55 例(15.3%)患者在治疗时年龄超过 75 岁。
在随访结束时,373 个游离皮瓣中有 360 个(96.5%)成功转移。整体重建并发症发生率为 31.4%(年轻组为 31.8%,其余患者为 29.1%)。29.2%的病例出现了医疗并发症(年龄小于 75 岁:28.8%;年龄大于 75 岁:30.9%)。ASA 状态与年龄小于 75 岁患者并发症发生率显著相关(p < 0.0001)。
与以往研究一致,本研究结果表明,游离组织转移可在高龄患者中获得高度技术成功。年龄不能作为重建决策的适当标准。相反,根据合并症和一般情况(ASA 状态)对患者进行仔细选择,对于降低术后并发症发生率和提高手术效果至关重要。