Nie Hong-ming, Chen Jian-jie, Wang Rong, Wang Cheng-bao, Dong Hui-lin, Chen Yi-yun
Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2012 May;33(5):501-4.
To understand the distribution of hepatitis C virus (HCV) genotypes in China.
A national multi-center, large sample epidemiological survey was carried out and certified by an international third-party testing organization. Internationally accepted method for sequencing analysis of viral genotype was used.
Patients were those suffered from the 4 major genotypes of chronic hepatitis C, including nine subtypes, which were dominated by genotype 1 (69.6%), with type 1b in particular (accounting for 68.38%). Among the rare gene-6, we saw more subtypes of 6a. In the south, central, and north areas, there was no significant difference seen between the south and the north areas in the distribution of the genotype 1. However, the rate of gene type 2a increased gradually from south to north. In terms of less common type of gene 3b and gene-6, they were seen mainly in the southern provinces.
In China, Patients with chronic hepatitis C had 4 HCV genotypes, with 9 subtypes. The rarely seen genotypes 3b and 6 were mainly distributed in the southern provinces.
了解中国丙型肝炎病毒（HCV）基因型的分布情况。
开展全国多中心、大样本流行病学调查，并由国际第三方检测机构认证。采用国际公认的病毒基因型测序分析方法。
患者为慢性丙型肝炎4种主要基因型感染者，包括9个亚型，以1型为主（69.6%），其中1b型尤为突出（占68.38%）。在罕见的6型基因中，6a亚型较多。在南方、中部和北方地区，1型基因型在南方和北方的分布无显著差异。然而，2a型基因的比例从南向北逐渐增加。就较少见的3b型基因和6型基因而言，它们主要见于南方省份。
在中国，慢性丙型肝炎患者有4种HCV基因型，9个亚型。少见的3b型和6型基因型主要分布在南方省份。
