School of Biochemistry, Medical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Cell Metab. 2012 Aug 8;16(2):141-3. doi: 10.1016/j.cmet.2012.07.013.
The mitochondrial pyruvate carrier (MPC) is essential for several major pathways of carbohydrate, fat, and amino acid metabolism, yet its molecular identity has remained elusive. Two recent papers in Science (Herzig et al., 2012; Bricker et al., 2012) implicate three newly identified inner mitochondrial membrane proteins as MPC components.
线粒体丙酮酸载体(MPC)对于碳水化合物、脂肪和氨基酸代谢的几个主要途径是必不可少的,但它的分子身份一直难以捉摸。最近在《科学》杂志上的两篇论文(Herzig 等人,2012 年;Bricker 等人,2012 年)表明,三种新鉴定的线粒体内膜蛋白是 MPC 的组成部分。