Christiaens J L
Service de neurochirurgie A, Centre hospitalier et universitaire, Lille.
Agressologie. 1990 May;31(5):241-2.
Results of subarachnoid hemorrhage (SAH) in the acute phase are represented by the direct threat of vasospasm. The first step still is to recognise SAH, so that all misleading clinical aspects of arterial aneurysm rupture do not misguide, or even fail to do the right diagnosis. If so, rebleeding still remains a real danger. Among biological patterns, hyponatremia is an important factor of vasospasm. Cardiovascular symptoms are represented by a sudden and transient arterial hypertension which can drive to a diagnostic error and electrocardiographic abnormalities, which are directly related with the degree of vasospasm; their evolution is completely regressive. Main intracranial consequences are early hydrocephalus, worsening of consciousness and progressive ventricular distension on CT scan and vasospasm, which occurs between the 4th and the 12th day, may be asymptomatic or symptomatic, responsive for delayed ischemia, followed by deterioration of consciousness and focal neurological signs. The main factors responsible for the vasospasm are a high amount of blood in basal cisterns on CT scan; an increase of substances released by the lysis of hemoglobin in CSF; hyponatremia, hypovolemia, and decrease in cerebral blood flow. Consequences of these disorders have to be well known in the medical treatment before and after operation.
蛛网膜下腔出血(SAH)急性期的结果表现为血管痉挛的直接威胁。首要步骤仍是识别SAH,以免动脉动脉瘤破裂所有具有误导性的临床特征造成误导,甚至导致误诊。如果这样,再出血仍然是一个实际存在的危险。在生物学模式中,低钠血症是血管痉挛的一个重要因素。心血管症状表现为突然和短暂的动脉高血压,这可能导致诊断错误以及心电图异常,而心电图异常与血管痉挛程度直接相关;其演变完全是退行性的。主要的颅内后果是早期脑积水、意识恶化以及CT扫描显示的进行性脑室扩张,血管痉挛发生在第4天至第12天之间,可能无症状或有症状,是迟发性缺血的原因,随后出现意识恶化和局灶性神经体征。导致血管痉挛的主要因素是CT扫描显示基底池内有大量血液;脑脊液中血红蛋白溶解释放的物质增加;低钠血症、血容量不足以及脑血流量减少。在手术前后的医疗过程中,必须充分了解这些病症的后果。