Wang Ze-hai, Lin Wen-sen, Li Shu-yan, Zhao Shao-cheng, Wang Li, Yang Zhong-gang, Chen Jie, Zhang Zhen-fu, Yu Jin-zhen
Department of Otorhinolaryngology Head and Neck Surgery, People's Hospital of Qingxian, Hebei Province, Qingxian 062650, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 May;47(5):379-82.
To obtain the prevalence of allergic rhinitis (AR) in different regions of northern China, to analyze the correlation and interaction between AR and bronchial asthma (BA) or atopic dermatitis (AD), and to provide reference for the prevention and treatment of allergic diseases such as AR.
To obtain the indexes including age, occupation, atopic physical fitness, smoking, alcohol, lifestyle and so on. To explore the correlation between AR and BA or AD. From April 2007 to May 2010, the serum specific IgE (sIgE) was investigated in different regions (rural areas of Qingxian, Hebei; coastal fishing village of Bohai Bay, Huanghua; area of Wuling Mountain, Chengde; urban areas of Tianjin) by randomly multi-stage and cluster sampling, with total population of 1524.
The prevalence of AR, BA and AD were 9.1%, 5.4% and 6.0%. The prevalence of BA and AD were 30.9% and 29.5% in AR patients, but were 2.9% and 3.7% in non-AR, and the differences were of statistical significance (χ(2) values were 192.97 and 148.40, respectively, all P < 0.01). The risk of people with BA suffering from AR was as 8.619 times as those free from BA, the risk of people with AD suffering from AR was as 1.817 times as those free from AD and, the risk of workers suffering from AR was as 2.320 times as farmers in terms of working factor by analysis of Logistic regression for AR and BA, AD, age, occupation, atopic physical fitness and other factors.
The prevalence of AR are correlated with BA and AD. It is greater between BA and AR than AD and AR in the strength of correlation.
了解中国北方不同地区变应性鼻炎（AR）的患病率，分析AR与支气管哮喘（BA）或特应性皮炎（AD）之间的相关性及相互作用，为AR等变应性疾病的防治提供参考。
获取年龄、职业、特应性体质、吸烟、饮酒、生活方式等指标，探讨AR与BA或AD之间的相关性。2007年4月至2010年5月，采用随机多阶段整群抽样方法，对河北青县农村、黄骅渤海湾沿海渔村、承德雾灵山地区、天津市区等不同地区1524人进行血清特异性IgE（sIgE）检测。
AR、BA和AD的患病率分别为9.1%、5.4%和6.0%。AR患者中BA和AD的患病率分别为30.9%和29.5%，非AR患者中BA和AD的患病率分别为2.9%和3.7%，差异有统计学意义（χ²值分别为192.97和148.40，均P<0.01）。通过对AR与BA、AD、年龄、职业、特应性体质等因素进行Logistic回归分析，结果显示患BA者患AR的风险是未患BA者的8.619倍，患AD者患AR的风险是未患AD者的1.817倍，就工作因素而言，职业为工人的人群患AR的风险是农民的2.320倍。
AR的患病率与BA和AD相关，BA与AR的相关性强度大于AD与AR的相关性强度。
