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复发性自然流产的发生率及其对后续婚姻关系和疾病的影响:日本冈崎队列研究

Frequency of recurrent spontaneous abortion and its influence on further marital relationship and illness: the Okazaki Cohort Study in Japan.

作者信息

Sugiura-Ogasawara Mayumi, Suzuki Sadao, Ozaki Yasuhiko, Katano Kinue, Suzumori Nobuhiro, Kitaori Tamao

机构信息

Departments of Obstetrics and Gynecology Public Health, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.

出版信息

J Obstet Gynaecol Res. 2013 Jan;39(1):126-31. doi: 10.1111/j.1447-0756.2012.01973.x. Epub 2012 Aug 13.

DOI:10.1111/j.1447-0756.2012.01973.x
PMID:22889462
Abstract

AIMS

The aim of this study was to examine the influence of recurrent spontaneous abortion (RSA) on marital relationships, and the association between past/present illness and RSA.

MATERIAL AND METHODS

A total of 2733 Japanese women who underwent a medical examination responded to the questionnaire.

RESULTS

The frequency of recurrent miscarriage and two or more consecutive RSA were 0.88% and 4.2%, respectively. Women with a history of miscarriages (hazard ratio: 1.596) and RSA (hazard ratio: 3.103) were at a higher risk of their relationships ending as compared with the women without a history of miscarriage. Existence of a relation was seen between a history of RSA and the occurrence of gastric ulcer, gastritis, fatty liver, and atopic dermatitis. Overall, 89.5% of the women with RSA experienced cumulative live births.

CONCLUSIONS

Miscarriage was found to be a severe life event with an influence on marital relationships, and to be associated with an elevated risk of gastric disease or atopic dermatitis.

摘要

目的

本研究旨在探讨复发性自然流产(RSA)对婚姻关系的影响,以及既往/当前疾病与RSA之间的关联。

材料与方法

共有2733名接受体检的日本女性对问卷进行了回复。

结果

复发性流产和两次或更多次连续RSA的发生率分别为0.88%和4.2%。有流产史的女性(风险比:1.596)和RSA女性(风险比:3.103)与没有流产史的女性相比,关系结束的风险更高。RSA史与胃溃疡、胃炎、脂肪肝和特应性皮炎的发生之间存在关联。总体而言,89.5%的RSA女性实现了累积活产。

结论

流产被发现是一个严重的生活事件,对婚姻关系有影响,并与胃病或特应性皮炎风险升高有关。

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