Maher K A, Deschner W K, Cattau E L, Benjamin S B
Gastroenterol Nurs. 1990 Summer;13(1):4-8.
Drug provocation is routinely used during esophageal manometry in the evaluation of chest pain of presumed esophageal origin. As significant side effects have been associated with the use of drugs in provocation, and these provocative tests are inadequately sensitive to exclude esophageal etiology as the cause of chest pain, alternative provocative tests have been sought. Intraesophageal balloon distention (IEBD) has recently been reintroduced as a method of pain provocation in the manometric evaluation of chest pain. IEBD produces pain on distention which resolves immediately on deflation. To evaluate graded IEBD as an effective and safe method of pain provocation, 66 consecutive patients presenting with chest pain and 10 asymptomatic volunteers were studied. We conclude that balloon distention is an effective and safe method of pain provocation and can easily be performed in conjunction with standard esophageal manometry.
在评估疑似食管源性胸痛时，药物激发试验在食管测压过程中经常被使用。由于在激发试验中使用药物会产生显著的副作用，并且这些激发试验对排除食管病因作为胸痛原因的敏感性不足，因此一直在寻找替代的激发试验。食管内气囊扩张术（IEBD）最近作为一种在胸痛测压评估中引发疼痛的方法被重新引入。IEBD在扩张时产生疼痛，放气后疼痛立即缓解。为了评估分级IEBD作为一种有效且安全的疼痛激发方法，对66例连续出现胸痛的患者和10名无症状志愿者进行了研究。我们得出结论，气囊扩张是一种有效且安全的疼痛激发方法，并且可以很容易地与标准食管测压联合进行。
