Scolozzi Paolo, Becker Minerva, Lombardi Tommaso
Hôpitaux Universitaires de Genève, Genève, Switzerland.
J Can Dent Assoc. 2012;78:c77.
Metastasis of a tumour to the mandibular condyle is rare. We describe a case in which a patient presented with isolated condylar metastasis mimicking acute internal derangement of the temporomandibular joint (TMJ). Open biopsy revealed a lesion seated within the condylar head and extending through the bony cortex to the infratemporal fossa. Histopathology confirmed the diagnosis of metastatic large-cell lung carcinoma. TMJ dysfunction may be associated with any pathologic entity involving the mandibular condyle. A panoramic radiograph should be considered in patients who do not respond to conventional therapy or whose clinical symptoms worsen. Particular attention must be paid to osteolytic jaw lesions, which can be the "tip of the iceberg" indicating widespread metastatic disease.
肿瘤转移至下颌髁突十分罕见。我们描述了一例患者,其表现为孤立的髁突转移,酷似颞下颌关节(TMJ)的急性内紊乱。开放活检显示病变位于髁突头部,并穿过骨皮质延伸至颞下窝。组织病理学确诊为转移性大细胞肺癌。TMJ功能障碍可能与任何累及下颌髁突的病理实体相关。对于对常规治疗无反应或临床症状恶化的患者,应考虑拍摄全景X线片。必须特别注意溶骨性颌骨病变,其可能是广泛转移性疾病的“冰山一角”。