McConnell Michael, Kumar Rajendra, Amini Behrang, Lin Patrick P, Wang Wei-Lien
Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, 1515- Holcombe Blvd, Unit 1475, Houston, TX, 77030, USA.
Department of Orthopaedic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Skeletal Radiol. 2017 Jan;46(1):123-127. doi: 10.1007/s00256-016-2504-6. Epub 2016 Oct 20.
We present the case of an 83-year-old man who had painful swelling of right knee for 6 months. Radiographs showed a large intra-articular soft-tissue mass with small calcifications, whereas MRI detected a multilobulated intra-articular tumor with bone erosions at the distal femur. Histopathology of ultrasound-guided biopsy specimen of the synovial mass revealed it to be a poorly differentiated metastatic carcinoma. Abdominal computed tomography with intravenous contrast medium administration found a heterogeneously enhancing large right renal mass with calcifications, which was shown to be a renal cell carcinoma on histopathology. No metastases were found elsewhere. To our knowledge, this is the first reported case with MRI findings of a calcified intra-articular synovial metastasis from renal cell carcinoma.
我们报告一例83岁男性,其右膝疼痛肿胀6个月。X线片显示关节内有一个伴有小钙化的大软组织肿块,而磁共振成像(MRI)检测到一个多叶状关节内肿瘤,股骨远端有骨质侵蚀。滑膜肿块超声引导下活检标本的组织病理学显示为低分化转移性癌。静脉注射造影剂的腹部计算机断层扫描发现右肾有一个不均匀强化的大肿块伴有钙化,组织病理学显示为肾细胞癌。其他部位未发现转移。据我们所知,这是首例报告的具有MRI表现的肾细胞癌钙化性关节内滑膜转移病例。