Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, No 386, Dazhong 1st Rd, Zuoying District, Kaohsiung City 81362, Taiwan, ROC.
Clin Nucl Med. 2012 Sep;37(9):899-900. doi: 10.1097/RLU.0b013e31825b271f.
A 58-year-old woman presented with shuffling gait with small steps for 3 months. Tc-TRODAT-1 dopamine transporter SPECT/CT was prescribed to detect the function of the nigrostriatal system. It disclosed absence of uptake in the left putamen and diffusely decreased uptake in the right striatum. An unexpected mass with uneven uptake over the right frontal lobe was also noted. MRI demonstrated a large dura-related tumor, which was later proved as a meningioma after surgical intervention. Meningioma is the most common cause of tumor-induced parkinsonism. This case points to the significance of functional and structural fused neuroimaging in the evaluation of parkinsonism.
一位 58 岁女性因步态蹒跚伴小碎步 3 个月就诊。Tc-TRODAT-1 多巴胺转运体 SPECT/CT 被开用来检测黑质纹状体系统的功能。结果显示左侧壳核摄取缺失,右侧纹状体弥漫性摄取减少。还注意到右侧额叶不均匀摄取的意外肿块。MRI 显示一个与硬脑膜相关的大型肿瘤,经手术干预后证实为脑膜瘤。脑膜瘤是引起帕金森病最常见的原因。本例提示功能和结构融合的神经影像学在帕金森病评估中的重要性。