Codner Pablo, Nevzorov Roman, Kusniec Jairo, Haim Moti, Zabarski Ronit, Strasberg Boris
Department of Cardiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel.
Isr Med Assoc J. 2012 Jun;14(6):343-6.
Defibrillation threshold (DFT) testing at the time of implantable cardioverter defibrillator (ICD) insertion is performed routinely. This practice is being reconsidered due to doubts about its ability to improve ICD efficacy and evidence that survival may not be affected by the test.
To compare the outcome of ICD recipients who underwent DFT testing and those who did not.
A total of 213 eligible patients were implanted with an ICD between 2004 and 2009. DFT testing was performed in 80 of them. We compared total mortality, appropriate and inappropriate ICD shocks, and anti-tachycardia pacing (ATP) events between DFT and non-DFT patients during a follow-up of 2 years.
On comparing the DFT and non-DFT groups, we found a 2 year mortality rate of 7.5% versus 8.3%, respectively (P = 0.8). Furthermore, 20.7% of patients in the DFT group and 12.4% in the non-DFT group had at least one episode of ICD shock (P = 0.15). With regard to ICD treatment (ICD shocks or ATP events), 57.7% in the DFT group and 64.2% in the non-DFT group received appropriate treatments (P = 0.78).
No significant differences in the incidence of 2 year mortality or percentage of ICD treatment emerged between the DFT and non-DFT groups.
在植入式心律转复除颤器（ICD）植入时常规进行除颤阈值（DFT）测试。由于对其改善ICD疗效的能力存在疑问以及有证据表明生存率可能不受该测试影响，这种做法正在重新审视。
比较接受DFT测试的ICD植入者和未接受DFT测试的ICD植入者的结局。
2004年至2009年间共有213例符合条件的患者植入了ICD。其中80例进行了DFT测试。我们比较了DFT组和非DFT组患者在2年随访期间的总死亡率、适当和不适当的ICD电击以及抗心动过速起搏（ATP）事件。
比较DFT组和非DFT组时，我们发现2年死亡率分别为7.5%和8.3%（P = 0.8）。此外，DFT组20.7%的患者和非DFT组12.4%的患者至少有一次ICD电击发作（P = 0.15）。关于ICD治疗（ICD电击或ATP事件），DFT组57.7%的患者和非DFT组64.2%的患者接受了适当治疗（P = 0.78）。
DFT组和非DFT组在2年死亡率发生率或ICD治疗百分比方面无显著差异。
