Department of Cardiology, Konya Teaching and Medical Research Center, Baskent University, Konya, Turkey.
Clin Exp Hypertens. 2013;35(3):183-91. doi: 10.3109/10641963.2012.712176. Epub 2012 Aug 14.
In this study, we have measured coronary flow reserve (CFR) using transthoracic echocardiography and brachial artery flow-mediated dilatation using vascular ultrasound in 36 subjects with masked hypertension (MH), 62 patients with sustained hypertension (SH), 40 patients with white-coat hypertension (WCH), and 39 healthy volunteers. CFR was significantly lower in the MH and SH groups (2.30 ± 0.39 and 2.28 ± 0.52, respectively) than in the control and WCH groups (2.85 ± 0.39 and 2.77 ± 0.41, respectively; P < .05). CFR was significantly impaired in patients with MH and SH compared with WCH and normotensive subjects. MH and SH groups are comparable with regard to cardiovascular risks and target organ damage.
在这项研究中，我们使用经胸超声心动图测量了 36 名隐匿性高血压（MH）患者、62 名持续性高血压（SH）患者、40 名白大衣高血压（WCH）患者和 39 名健康志愿者的冠状动脉血流储备（CFR），并使用血管超声测量了肱动脉血流介导的扩张。MH 和 SH 组的 CFR 明显低于对照组和 WCH 组（分别为 2.30±0.39 和 2.28±0.52，分别为 2.85±0.39 和 2.77±0.41；P<.05）。与 WCH 和血压正常的受试者相比，MH 和 SH 患者的 CFR 明显受损。MH 和 SH 组在心血管风险和靶器官损害方面相当。
