Department of Neurological and Psychiatric Sciences, University of Florence, Florence, Italy.
Eur J Neurol. 2012 Sep;19(9):1159-79. doi: 10.1111/j.1468-1331.2012.03784.x.
The last version of the EFNS dementia guidelines is from 2007. In 2010, the revised guidelines for Alzheimer's disease (AD) were published. The current guidelines involve the revision of the dementia syndromes outside of AD, notably vascular cognitive impairment, frontotemporal lobar degeneration, dementia with Lewy bodies, corticobasal syndrome, progressive supranuclear palsy, Parkinson's disease dementia, Huntington's disease, prion diseases, normal-pressure hydrocephalus, limbic encephalitis and other toxic and metabolic disorders. The aim is to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists and other specialist physicians responsible for the care of patients with dementing disorders. It represents a statement of minimum desirable standards for practice guidance.
The task force working group reviewed evidence from original research articles, meta-analyses and systematic reviews, published by June 2011. The evidence was classified (I, II, III, IV) and consensus recommendations graded (A, B, or C) according to the EFNS guidance. Where there was a lack of evidence, but clear consensus, good practice points were provided.
New recommendations and good practice points are made for clinical diagnosis, blood tests, neuropsychology, neuroimaging, electroencephalography, cerebrospinal fluid (CSF) analysis, genetic testing, disclosure of diagnosis, treatment of behavioural and psychological symptoms in dementia, legal issues, counselling and support for caregivers. All recommendations were revised as compared with the previous EFNS guidelines. The specialist neurologist together with primary care physicians play an important role in the assessment, interpretation and treatment of symptoms, disability and needs of dementia patients.
欧洲神经病学会（EFNS）的最新一版痴呆症指南是在 2007 年发布的。2010 年，阿尔茨海默病（AD）修订版指南发布。当前的指南涉及到 AD 以外的痴呆综合征的修订，特别是血管性认知障碍、额颞叶痴呆、路易体痴呆、皮质基底节综合征、进行性核上性麻痹、帕金森病痴呆、亨廷顿病、朊病毒病、正常压力脑积水、边缘性脑炎和其他毒性和代谢性疾病。目的是为临床神经科医生、老年病学家、精神科医生和其他负责痴呆患者护理的专科医生提供一份经过同行评审的基于证据的声明，以指导实践。它代表了实践指导最低理想标准的陈述。
工作组审查了截至 2011 年 6 月发表的原始研究文章、荟萃分析和系统评价的证据。根据 EFNS 指南对证据进行分类（I、II、III、IV）并对共识建议进行分级（A、B 或 C）。在缺乏证据但有明确共识的情况下，提供了良好的实践要点。
针对临床诊断、血液检查、神经心理学、神经影像学、脑电图、脑脊液（CSF）分析、基因检测、诊断披露、痴呆患者行为和心理症状的治疗、法律问题、对护理人员的咨询和支持，提出了新的建议和良好的实践要点。与之前的 EFNS 指南相比，所有建议都进行了修订。专科神经科医生与初级保健医生一起，在评估、解释和治疗痴呆患者的症状、残疾和需求方面发挥着重要作用。
