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原发性干燥综合征与自身免疫性血细胞减少症:一种常被忽视的关系。

Primary Sjogren's syndrome and autoimmune cytopenias: a relation often overlooked.

作者信息

Khattri Saakshi, Barland Peter

机构信息

Division of Rheumatology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

出版信息

Bull NYU Hosp Jt Dis. 2012;70(2):130-2.

PMID:22892005
Abstract

Primary Sjogren's syndrome is an autoimmune disease wherein there is lymphocytic infiltration of salivary and lacrimal glands. This inflammation is thought to be caused by B-lymphocytes. The most common clinical feature of Sjogren's is dryness of the mouth and eyes, but rare complications can occur such as autoimmune cytopenias. Here we report two cases of immune mediated cytopenias that were diagnosed to be due to Sjogren's syndrome. In both cases, immune suppressive treatment was required.

摘要

原发性干燥综合征是一种自身免疫性疾病,其特征为唾液腺和泪腺出现淋巴细胞浸润。这种炎症被认为是由B淋巴细胞引起的。干燥综合征最常见的临床特征是口干和眼干,但也可能出现罕见的并发症,如自身免疫性血细胞减少症。在此,我们报告两例被诊断为由干燥综合征引起的免疫介导性血细胞减少症病例。在这两个病例中,均需要进行免疫抑制治疗。

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Bull NYU Hosp Jt Dis. 2012;70(2):130-2.
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Ann Transl Med. 2022 Mar;10(6):300. doi: 10.21037/atm-22-162.
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How to Distinguish Patients with pSS among Individuals with Dryness without Invasive Diagnostic Studies.
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J Immunol Res. 2018 May 2;2018:1060421. doi: 10.1155/2018/1060421. eCollection 2018.
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A retrospective study of long-term outcomes in 152 patients with primary Sjogren's syndrome: 25-year experience.原发性干燥综合征 152 例患者长期预后的回顾性研究:25 年经验。
Clin Med (Lond). 2014 Apr;14(2):157-64. doi: 10.7861/clinmedicine.14-2-157.