Yurtdaş Mustafa, Aydin Mehmet Kasim
Department of Cardiology, Lokman Hekim Hospital, Turkey.
Intern Med. 2012;51(16):2161-4. doi: 10.2169/internalmedicine.51.7852. Epub 2012 Aug 15.
Kounis syndrome has been known as allergenic angina and/or allergenic myocardial infarction following an allergic reaction. Probable allergic insults usually include drugs, latex, and food. Although ceftriaxone administration has been associated with various allergic reactions such as urticaria, angioedema, erythema, rash and anaphylactic shock, as far as we know, there is no published report that has shown an association between ceftriaxone use and Kounis syndrome. Here, we describe the first report of allergic vasospasm, culminating in acute inferior myocardial infarction, probably as the result of an acute allergenic reaction, after ceftriaxone use.
库尼斯综合征一直被认为是过敏反应后出现的过敏性心绞痛和/或过敏性心肌梗死。可能的过敏诱因通常包括药物、乳胶和食物。尽管使用头孢曲松已与各种过敏反应相关,如荨麻疹、血管性水肿、红斑、皮疹和过敏性休克,但据我们所知,尚无已发表的报告表明使用头孢曲松与库尼斯综合征之间存在关联。在此,我们描述了首例在使用头孢曲松后发生过敏性血管痉挛,最终导致急性下壁心肌梗死的报告,这可能是急性过敏反应的结果。