Wada Tadashi, Abe Mitsuru, Yagi Nobuhito, Kokubu Nobuaki, Kasahara Yoichiro, Kataoka Yu, Otsuka Yoritaka, Goto Yoichi, Nonogi Hiroshi
Division of Cardiology, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565-8565, Japan.
Heart Vessels. 2010 May;25(3):263-6. doi: 10.1007/s00380-009-1187-5. Epub 2010 May 29.
Coronary vasospasm can be induced by allergic reactions with some chemical mediators, and the angina and myocardial infarction secondary to allergy-induced coronary vasospasm are referred to as "Kounis syndrome." Only two cases of Kounis syndrome following food ingestion have been reported. However, they had pre-existing atheromatous coronary artery disease, and no provocation test to induce coronary vasospasm was done. We describe here another probable case of allergic vasospasm after food intake. To the best of our knowledge, this is the first documented report of a patient with food-induced allergic vasospasm subsequent to the provocation test with ergometrine maleate.
冠状动脉痉挛可由某些化学介质的过敏反应诱发，继发于过敏诱导的冠状动脉痉挛的心绞痛和心肌梗死被称为“库尼斯综合征”。仅报道过两例食物摄入后发生库尼斯综合征的病例。然而，这两例患者均有动脉粥样硬化性冠状动脉疾病史，且未进行诱发冠状动脉痉挛的激发试验。我们在此描述另一例食物摄入后可能发生过敏痉挛的病例。据我们所知，这是第一例在使用马来酸麦角新碱激发试验后出现食物诱发过敏痉挛的患者的文献报道。
